Lonapegsomatropin Dosage
Medically reviewed by Drugs.com. Last updated on Mar 4, 2025.
Applies to the following strengths: tcgd 3 mg; tcgd 3.6 mg; tcgd 4.3 mg; tcgd 5.2 mg; tcgd 6.3 mg; tcgd 7.6 mg; tcgd 9.1 mg; tcgd 11 mg; tcgd 13.3 mg
Usual Pediatric Dose for:
Additional dosage information:
Usual Pediatric Dose for Pediatric Growth Hormone Deficiency
1 year and older and weighing at least 11.5 kg:
Recommended dose: 0.24 mg/kg subcutaneously once a week
Comments:
- Individualize dose based on response.
- Round dose to closest cartridge dose while considering treatment goals and patient response.
- If no increase in height velocity, particularly during the first year of treatment, assess compliance and evaluate other causes of poor growth such as hypothyroidism, undernutrition, advanced bone age and antibodies to recombinant human growth hormone.
- Discontinue once epiphyseal fusion has occurred.
Use: Treatment of pediatric patients 1 year and older who weigh at least 11.5 kg and have growth failure due to inadequate secretion of endogenous growth hormone (GH)
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
- Acute critical illness
- Hypersensitivity to any of the ingredients
- Children with closed epiphyses
- Active malignancy
- Active proliferative or severe non-proliferative diabetic retinopathy
- Children with Prader-Willi syndrome who are severely obese or have severe respiratory impairment due to risk of sudden death
Safety and efficacy have not been established in patients younger than 1 year; this drug is not recommended for use in these patients.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Rotate administration site to avoid lipoatrophy.
Monitoring:
- Therapy should be supervised by a physician experienced in the diagnosis and management of pediatric growth failure due to growth hormone deficiency (GHD).
- To exclude preexisting papilledema, perform fundoscopic examination before initiating treatment and reassess periodically thereafter.
More about lonapegsomatropin
- Check interactions
- Compare alternatives
- Side effects
- During pregnancy
- Drug class: growth hormones
- Breastfeeding
- En español
Patient resources
Other brands
Professional resources
Other brands
Related treatment guides
See also:
Ngenla
Ngenla is a long-acting human growth hormone used to treat children aged 3 and older who are not ...
Humatrope
Humatrope injection (somatropin) is a human growth hormone used to treat growth failure in children ...
Sogroya
Sogroya information from Drugs.com, includes Sogroya side effects, interactions and indications.
Genotropin
Genotropin is a human growth hormone used to treat growth failure in children and adults who lack ...
Norditropin
Norditropin is used to treat growth hormone deficiency (GHD) in adults and children and other ...
Omnitrope
Omnitrope (somatropin) is a form of human growth hormone used to treat adults and children with ...
Norditropin FlexPro
Norditropin FlexPro is used for adult human growth hormone deficiency, idiopathic short stature ...
Skytrofa
Skytrofa injection is a once-weekly, slow-release human growth hormone (lonapegsomatropin) ...
Nutropin
Nutropin is used for adult human growth hormone deficiency, growth retardation, chronic renal ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.