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Hydroxyamphetamine / Tropicamide Ophthalmic Dosage

Applies to the following strengths: 1%-0.25%

Usual Adult Dose for Pupillary Dilation

Instill 1 to 2 drops in the conjunctival sac(s) once


  • Onset of action typically occurs within 15 minutes, with maximum effect reached within 60 minutes.
  • Mydriasis should reverse spontaneously, usually within 6 to 8 hours, however, complete recovery may take up to 24 hours in some cases.
  • Clinically significant dilation, inhibition of pupillary light response, and partial cycloplegia may last about 3 hours.

Use: For the production of mydriasis in routine diagnostic procedures and in conditions where short term pupil dilation is desired

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for dosing related precautions.


Data not available

Other Comments

Administration advice:

  • For topical ophthalmic administration only; not for injection.

Storage requirements:
  • Protect from light.

  • Effectiveness may differ slightly in patients with light and dark irides, with those with light irides experiencing a slightly greater mydriasis.

Patient advice:
  • Do not to touch dropper tip to any surface to prevent solution contamination.
  • Avoid driving or operating heavy machinery while the pupils are dilated.
  • Protect eyes during bright illumination when pupils are dilated.
  • May experience photophobia and/or blurred vision.
  • Wash hands following administration.

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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.