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Ferriprox Dosage

Medically reviewed by Drugs.com. Last updated on June 1, 2020.

Generic name: DEFERIPRONE 500mg
Dosage form: tablet, film coated

Recommended Dosage

Starting Dose

The recommended initial dose of FERRIPROX is 25 mg/kg actual body weight, orally, three times per day for a total of 75 mg/kg/day. Round dose to the nearest 250 mg (half-tablet).

Table 1a: Tablet requirement to achieve a 25 mg/kg dose (rounded to the nearest half-tablet) for administration three times a day.
Body Weight (kg) Dose (mg) Number of 500 mg tablets
20 500 1
30 750 1.5
40 1,000 2
50 1,250 2.5
60 1,500 3
70 1,750 3.5
80 2,000 4
90 2,250 4.5

Dose Adjustments

Tailor dose adjustments to the individual patient’s response and therapeutic goals (maintenance or reduction of body iron burden). The maximum dose is 33 mg/kg actual body weight, three times per day for a total of 99 mg/kg/day.

Table 1b: Tablet requirement to achieve a 33 mg/kg dose (rounded to the nearest half-tablet) for administration three times a day.
Body Weight (kg) Dose (mg) Number of 500 mg tablets
20 660 1.5
30 990 2
40 1,320 2.5
50 1,650 3.5
60 1,980 4
70 2,310 4.5
80 2,640 5.5
90 2,970 6

Monitor serum ferritin concentration every two to three months to assess the effect of FERRIPROX on body iron stores. If the serum ferritin is consistently below 500 mcg/L, consider temporarily interrupting FERRIPROX therapy until serum ferritin rises above 500 mcg/L.

Dosage Modification for Drug Interactions

Allow at least a 4-hour interval between administration of FERRIPROX and other drugs or supplements containing polyvalent cations such as iron, aluminum, or zinc [see Drug Interactions (7.2 ), Clinical Pharmacology (12.3)].

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.