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Ergocalciferol Dosage

Medically reviewed by Drugs.com. Last updated on Mar 1, 2023.

Applies to the following strengths: 200 mcg/mL; 50,000 intl units; 500000 intl units/mL; 625 mcg; 50 mcg; 10 mcg

Usual Adult Dose for:

Usual Geriatric Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Hypoparathyroidism

50,000 to 200,000 international units (1250 to 5000 mcg) orally daily, concomitantly with calcium lactate 4 g, six times per day

Comments:

  • The range between therapeutic and toxic doses is narrow.
  • Dosage must be individualized under close medical supervision.
  • Calcium intake should be adequate.
  • Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.

Usual Adult Dose for Rickets

12,000 to 500,000 international units (300 to 12,500 mcg) orally daily

Comments:

  • The range between therapeutic and toxic doses is narrow.
  • Dosage must be individualized under close medical supervision.
  • Calcium intake should be adequate.
  • Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
  • X-ray bones monthly until condition is corrected and stabilized.

Usual Adult Dose for Familial Hypophosphatemia

12,000 to 500,000 international units (300 to 12,500 mcg) orally daily

Comments:

  • The range between therapeutic and toxic doses is narrow.
  • Dosage must be individualized under close medical supervision.
  • Calcium intake should be adequate.
  • Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
  • X-ray bones monthly until condition is corrected and stabilized.

Usual Adult Dose for Vitamin/Mineral Supplementation

Recommended Daily Allowance: 15 mcg (600 international units) daily
Tolerable Upper Intake Level: 100 mcg (4000 international units) daily

Usual Geriatric Dose for Vitamin/Mineral Supplementation

Recommended Daily Allowance:
Up to 70 years: 15 mcg (600 international units) orally daily
Over 70 years: 20 mcg (800 international units) orally daily

Tolerable Upper Intake Level: 100 mcg (4000 international units) daily

Usual Pediatric Dose for Rickets

12,000 to 500,000 international units (300 to 12,500 mcg) orally daily

Comments:

  • Pediatric doses must be individualized.
  • The range between therapeutic and toxic doses is narrow.
  • Dosage must be individualized under close medical supervision.
  • Calcium intake should be adequate.
  • Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
  • X-ray bones monthly until condition is corrected and stabilized.

Usual Pediatric Dose for Familial Hypophosphatemia

12,000 to 500,000 international units (300 to 12,500 mcg) orally daily

Comments:

  • Pediatric doses must be individualized.
  • The range between therapeutic and toxic doses is narrow.
  • Dosage must be individualized under close medical supervision.
  • Calcium intake should be adequate.
  • Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
  • X-ray bones monthly until condition is corrected and stabilized.

Usual Pediatric Dose for Hypoparathyroidism

50,000 to 200,000 international units (1250 to 5000 mcg) orally daily, concomitantly with calcium lactate 4 g, six times per day

Comments:

  • Pediatric doses must be individualized.
  • The range between therapeutic and toxic doses is narrow.
  • Dosage must be individualized under close medical supervision.
  • Calcium intake should be adequate.
  • Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.

Usual Pediatric Dose for Vitamin/Mineral Supplementation

Recommended Daily Allowance:
0 to 12 months: 10 mcg (400 international units) orally daily
1 year and older: 15 mcg (600 international units) orally daily

Tolerable Upper Intake Level:

  • 0 to 6 months: 25 mcg (1000 international units) daily
  • 7 to 12 months: 38 mcg (1500 international units) daily
  • 1 to 3 years: 63 mcg (2500 international units) daily
  • 4 to 8 years: 75 mcg (3000 international units) daily
  • 9 years and older: 100 mcg (4000 international units) daily

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Pregnancy/Lactation:

  • The US Recommended Daily Allowance for pregnancy or lactation is 15 mcg (600 international units) per day.
  • The Tolerable Upper Intake Level for pregnancy or lactation is 100 mcg (4000 international units) per day.

Dialysis

Data not available

Other Comments

Storage requirements:

  • Store at controlled room temperature

General:
  • The range between therapeutic and toxic doses is narrow.
  • The effects of vitamin D can persist for 2 or more months after cessation of treatment.

Monitoring:
  • Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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