Ergocalciferol Dosage

Medically reviewed by Drugs.com. Last updated on Oct 3, 2023.

Usual Adult Dose for Hypoparathyroidism

50,000 to 200,000 international units (1250 to 5000 mcg) orally daily, concomitantly with calcium lactate 4 g, six times per day

Comments:

• The range between therapeutic and toxic doses is narrow.
• Dosage must be individualized under close medical supervision.
• Calcium intake should be adequate.
• Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.

Usual Adult Dose for Rickets

12,000 to 500,000 international units (300 to 12,500 mcg) orally daily

Comments:

• The range between therapeutic and toxic doses is narrow.
• Dosage must be individualized under close medical supervision.
• Calcium intake should be adequate.
• Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
• X-ray bones monthly until condition is corrected and stabilized.

Usual Adult Dose for Familial Hypophosphatemia

12,000 to 500,000 international units (300 to 12,500 mcg) orally daily

Comments:

• The range between therapeutic and toxic doses is narrow.
• Dosage must be individualized under close medical supervision.
• Calcium intake should be adequate.
• Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
• X-ray bones monthly until condition is corrected and stabilized.

Usual Adult Dose for Vitamin/Mineral Supplementation

Recommended Daily Allowance: 15 mcg (600 international units) daily
Tolerable Upper Intake Level: 100 mcg (4000 international units) daily

Usual Geriatric Dose for Vitamin/Mineral Supplementation

Recommended Daily Allowance:
Up to 70 years: 15 mcg (600 international units) orally daily
Over 70 years: 20 mcg (800 international units) orally daily

Tolerable Upper Intake Level: 100 mcg (4000 international units) daily

Usual Pediatric Dose for Rickets

12,000 to 500,000 international units (300 to 12,500 mcg) orally daily

Comments:

• Pediatric doses must be individualized.
• The range between therapeutic and toxic doses is narrow.
• Dosage must be individualized under close medical supervision.
• Calcium intake should be adequate.
• Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
• X-ray bones monthly until condition is corrected and stabilized.

Usual Pediatric Dose for Familial Hypophosphatemia

12,000 to 500,000 international units (300 to 12,500 mcg) orally daily

Comments:

• Pediatric doses must be individualized.
• The range between therapeutic and toxic doses is narrow.
• Dosage must be individualized under close medical supervision.
• Calcium intake should be adequate.
• Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
• X-ray bones monthly until condition is corrected and stabilized.

Usual Pediatric Dose for Hypoparathyroidism

50,000 to 200,000 international units (1250 to 5000 mcg) orally daily, concomitantly with calcium lactate 4 g, six times per day

Comments:

• Pediatric doses must be individualized.
• The range between therapeutic and toxic doses is narrow.
• Dosage must be individualized under close medical supervision.
• Calcium intake should be adequate.
• Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.

Usual Pediatric Dose for Vitamin/Mineral Supplementation

Recommended Daily Allowance:
0 to 12 months: 10 mcg (400 international units) orally daily
1 year and older: 15 mcg (600 international units) orally daily

Tolerable Upper Intake Level:

• 0 to 6 months: 25 mcg (1000 international units) daily
• 7 to 12 months: 38 mcg (1500 international units) daily
• 1 to 3 years: 63 mcg (2500 international units) daily
• 4 to 8 years: 75 mcg (3000 international units) daily
• 9 years and older: 100 mcg (4000 international units) daily

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Pregnancy/Lactation:

• The US Recommended Daily Allowance for pregnancy or lactation is 15 mcg (600 international units) per day.
• The Tolerable Upper Intake Level for pregnancy or lactation is 100 mcg (4000 international units) per day.

Dialysis

Data not available

Other Comments

Storage requirements:

• Store at controlled room temperature

General:

• The range between therapeutic and toxic doses is narrow.
• The effects of vitamin D can persist for 2 or more months after cessation of treatment.

Monitoring:

• Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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