Ergocalciferol Dosage

Usual Adult Dose for Hypoparathyroidism

50,000 to 200,000 international units orally daily, concomitantly with calcium lactate 4 g, six times per day

Comments:
-The range between therapeutic and toxic doses is narrow.
-Dosage must be individualized under close medical supervision.
-Calcium intake should be adequate.
-Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.

Usual Adult Dose for Rickets

12,000 to 500,000 international units orally daily

Comments:
-The range between therapeutic and toxic doses is narrow.
-Dosage must be individualized under close medical supervision.
-Calcium intake should be adequate.
-Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
-X-ray bones monthly until condition is corrected and stabilized.

Usual Adult Dose for Familial Hypophosphatemia

12,000 to 500,000 international units orally daily

Comments:
-The range between therapeutic and toxic doses is narrow.
-Dosage must be individualized under close medical supervision.
-Calcium intake should be adequate.
-Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
-X-ray bones monthly until condition is corrected and stabilized.

Usual Adult Dose for Vitamin/Mineral Supplementation

Recommended Daily Allowance: 600 international units daily
Tolerable Upper Intake Level: 4000 international units daily

Usual Geriatric Dose for Vitamin/Mineral Supplementation during Pregnancy/Lactation

Recommended Daily Allowance:
Up to 70 years:600 international units orally daily
Over 70 years: 800 international units orally daily

Tolerable Upper Intake Level: 4000 international units daily

Usual Pediatric Dose for Rickets

12,000 to 500,000 international units orally daily

Comments:
-Pediatric doses must be individualized.
-The range between therapeutic and toxic doses is narrow.
-Dosage must be individualized under close medical supervision.
-Calcium intake should be adequate.
-Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
-X-ray bones monthly until condition is corrected and stabilized.

Usual Pediatric Dose for Familial Hypophosphatemia

12,000 to 500,000 international units orally daily

Comments:
-Pediatric doses must be individualized.
-The range between therapeutic and toxic doses is narrow.
-Dosage must be individualized under close medical supervision.
-Calcium intake should be adequate.
-Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.
-X-ray bones monthly until condition is corrected and stabilized.

Usual Pediatric Dose for Hypoparathyroidism

50,000 to 200,000 international units orally daily, concomitantly with calcium lactate 4 g, six times per day

Comments:
-Pediatric doses must be individualized.
-The range between therapeutic and toxic doses is narrow.
-Dosage must be individualized under close medical supervision.
-Calcium intake should be adequate.
-Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.

Usual Pediatric Dose for Vitamin/Mineral Supplementation

Recommended Daily Allowance:
0 to 12 months: 400 international units orally daily
1 year and older: 600 international units orally daily

Tolerable Upper Intake Level:
-0 to 6 months: 1000 international units daily
-7 to 12 months: 1500 international units daily
-1 to 3 years: 2500 international units daily
-4 to 8 years: 3000 international units daily
-9 years and older: 4000 international units daily

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

-The US Recommended Daily Allowance for pregnant or lactating women is 600 international units per day.
-The Tolerable Upper Intake Level for pregnant or lactating women is 4000 international units per day.

Dialysis

Data not available

Other Comments

Storage requirements:
-Store at controlled room temperature

General:
-The range between therapeutic and toxic doses is narrow.
-The effects of vitamin D can persist for 2 or more months after cessation of treatment.

Monitoring:
-Monitor blood calcium and phosphorus every 2 weeks, or more frequently if necessary.