Relenza (zanamivir) Disease Interactions
There is 1 disease interaction with Relenza (zanamivir):
Zanamivir (Includes Relenza) ↔ Asthma/Copd
Severe Potential Hazard, Moderate plausibility
Applies to: Asthma, Chronic Obstructive Pulmonary Disease
Serious respiratory adverse events, including bronchospasm and/or decline in lung function, have been reported during clinical trials and postmarketing use of zanamivir. The manufacturer does not generally recommend its use in patients with underlying airways disease such as asthma or chronic obstructive pulmonary disease. However, if it is prescribed, these patients should have a fast-acting inhaled bronchodilator readily available whenever zanamivir is administered. The drug should be stopped and the physician notified in case of worsening respiratory symptoms. Patients scheduled to use an inhaled bronchodilator at the same time as the zanamivir dose should use their bronchodilator before administering zanamivir.
- "Product Information. Relenza (zanamivir)" Glaxo Wellcome, Research Triangle Pk, NC.
Relenza (zanamivir) drug Interactions
There are 3 drug interactions with Relenza (zanamivir)
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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