Valstar Disease Interactions
There are 2 disease interactions with Valstar (valrubicin).
Valrubicin (applies to Valstar) perforated bladder
Major Potential Hazard, Moderate plausibility. Applicable conditions: Rupture of Bladder
Valrubicin is contraindicated in patients with perforated bladder or compromised bladder mucosa, including small bladder capacity that is unable to tolerate a 75 mL instillation. Evaluate the bladder before the intravesical instillation for severe irritable bladder symptoms, and in case of bladder perforation, delay the administration until bladder integrity has been restored. If this agent is administered to patients with bladder rupture or if perforation is suspected, significant systemic exposure may occur following intravesical administration and myelosuppression is possible. Weekly monitoring of complete blood counts should be performed for 3 weeks.
Valrubicin (applies to Valstar) urinary infection
Major Potential Hazard, Moderate plausibility. Applicable conditions: Urinary Tract Infection
Valrubicin is contraindicated in patients with current urinary tract infection.
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Valstar drug interactions
There are 6 drug interactions with Valstar (valrubicin).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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