Reltone (ursodiol) Disease Interactions
There are 2 disease interactions with Reltone (ursodiol):
Ursodiol (Includes Reltone) biliary obstruction
Major Potential Hazard, Moderate plausibility. Applies to: Biliary Obstruction
The use of ursodiol is contraindicated in patients with compelling reasons for cholecystectomy including unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis, or biliary gastrointestinal fistula.
Ursodiol (Includes Reltone) hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applies to: Liver Disease
Ursodiol therapy has not been associated with liver damage. However, patients given ursodiol should have liver function tests and bilirubin levels measured at the initiation of therapy and every month for three months after start of therapy, and every six months thereafter as appropriate. Close monitoring should be exercised in patients with liver impairment. Treatment discontinuation should be considered if the above parameters increase to a level considered clinically significant.
Reltone (ursodiol) drug interactions
There are 4 drug interactions with Reltone (ursodiol)
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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