Kanuma (sebelipase alfa) Disease Interactions
There are 2 disease interactions with Kanuma (sebelipase alfa):
Lysosomal enzymes (applies to Kanuma) hypersensitivity
Major Potential Hazard, Moderate plausibility. Applicable conditions: Pulmonary Impairment, Heart Disease
Patients with acute underlying respiratory illness or compromised cardiac and/or respiratory function may be at risk of serious exacerbation of their cardiac or respiratory symptoms due to hypersensitivity reactions during enzyme replacement therapy. Evaluation of cardiac function and airway patency should be considered before initiation of treatment. Appropriate medical support and monitoring measures should be readily available during enzyme replacement therapy, and some patients may require prolonged observation times that should be individualized based on the needs of the patient. Consider the risks and benefits of re-administering these agents following a severe reaction. Monitor patients, with appropriate resuscitation measures available, if the decision is made to re-administer the product.
Sebelipase alfa (applies to Kanuma) hypersensitivity
Major Potential Hazard, Moderate plausibility. Applicable conditions: Anaphylaxis
Kanuma, the brand name of sebelipase alfa injection is produced in the egg whites of genetically engineered chickens. It is recommended to consider the risks and benefits of treatment in patients with known systemic hypersensitivity reactions to eggs or egg products.
More about Kanuma (sebelipase alfa)
- Side Effects
- During Pregnancy
- Dosage Information
- Pricing & Coupons
- En Español
- Drug class: lysosomal enzymes
- FDA Approval History
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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