Sebelipase Alfa Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the clinical use of sebelipase alfa during breastfeeding. Because it is a large protein molecule with a molecular weight of about 55,000 Da, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. If sebelipase alfa is required by the mother, it is not a reason to discontinue breastfeeding. Until more data are available, sebelipase alfa should be used with infant careful monitoring during breastfeeding.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Sebelipase Alfa
CAS Registry Number
1276027-63-4
Drug Class
Breast Feeding
Lactation
Milk, Human
Enzymes
Sterol Esterase
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
