Lamzede

Generic name: velmanase alfa
Drug class: Lysosomal enzymes

Medically reviewed by Drugs.com on Oct 30, 2023. Written by Cerner Multum.

What is Lamzede?

Lamzede is used to treat some symptoms of alpha-mannosidosis (a genetic condition where the body is unable to break down complex sugars) in adults and children.

Lamzede may also be used for purposes not listed in this medication guide.

Lamzede side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your medical caregiver if you feel dizzy, nauseated, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.

Common side effects of Lamzede may include:

• fever;

• headache;

• joint pain;

• cold symptoms such as stuffy nose, sneezing, sore throat; or

• hives, difficult breathing, swelling of your face, lips, tongue, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Before taking this medicine

You may need to have a negative pregnancy test before starting this treatment.

May harm an unborn baby. Use effective birth control while using Lamzede and for at least 14 days after your last dose. Tell your doctor if you become pregnant.

Ask a doctor if it is safe to breastfeed while using Lamzede.

How is Lamzede given?

Lamzede is injected into a vein over a period of time by a healthcare provider.

Doses are based on weight. Your dose may change if you gain or lose weight.

You may be given other medications to help prevent serious side effects or allergic reaction. Keep taking these medicines for as long as your doctor has prescribed.

Store at room temperature away from moisture, heat, and light. Do not freeze.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Lamzede.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid while receiving Lamzede?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect Lamzede?

Other drugs may affect Lamzede, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Lamzede Biosimilars

Biosimilar and interchangeable products are biological products that are highly similar to and have no clinically meaningful differences from the reference product.

Reference products

These are biological products that have already been approved by the FDA, against which biosimilar products are compared. There is 1 for Lamzede.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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