Rasburicase Disease Interactions
There is 1 disease interaction with rasburicase:
Pegloticase/Rasburicase (Includes Rasburicase) ↔ G6Pd Deficiency
Severe Potential Hazard, High plausibility
Applies to: G-6-PD Deficiency
The antihyperuricemic agents pegloticase and rasburicase are contraindicated in patients deficient in glucose-6-phosphate-dehydrogenase (G6PD), as these have shown to cause severe hemolytic reactions and methemoglobinemia. Patients at high risk of G6PD deficiency such as patients of African, Mediterranean or Southern Asian ancestry, should be screened prior to starting treatment. Treatment with any of these drugs should be discontinued immediately and permanently in any patient developing hemolysis or methemoglobinemia.
rasburicase drug Interactions
There are 7 drug interactions with rasburicase
More about rasburicase
- Rasburicase Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- Drug class: antihyperuricemic agents
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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