Sohonos Disease Interactions
There are 3 disease interactions with Sohonos (palovarotene).
Palovarotene (applies to Sohonos) liver disease
Moderate Potential Hazard, Moderate plausibility.
The use of palovarotene in patients with moderate (Child-Pugh B) and severe hepatic impairment (Child-Pugh C) has not been evaluated. The use of this drug in these patients is not recommended.
References
- (2023) "Product Information. Sohonos (palovarotene)." Ipsen Biopharmaceuticals, Inc
Palovarotene (applies to Sohonos) psychiatric illness
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Depression, Psychosis, History - Psychiatric Disorder
Patients with a history of psychiatric illness may be more susceptible to the adverse effects including depression, anxiety, mood alterations and suicidal thoughts and behaviors. Monitor closely for development of new or worsening psychiatric symptoms during treatment.
References
- (2023) "Product Information. Sohonos (palovarotene)." Ipsen Biopharmaceuticals, Inc
Palovarotene (applies to Sohonos) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
The use of palovarotene in patients with severe renal impairment (ClCr 15 to 29 mL/min) is not recommended.
References
- (2023) "Product Information. Sohonos (palovarotene)." Ipsen Biopharmaceuticals, Inc
Sohonos drug interactions
There are 194 drug interactions with Sohonos (palovarotene).
Sohonos alcohol/food interactions
There is 1 alcohol/food interaction with Sohonos (palovarotene).
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.