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Nipocalimab Disease Interactions

There are 2 disease interactions with nipocalimab.

Moderate

Nipocalimab (applies to nipocalimab) active or latent infection

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral

Nipocalimab may increase the risk of infection. Serious infections occurred in 7% of patients. Treatment with nipocalimab should be delayed in patients with an active infection until resolved. Nipocalimab may also reactivate latent viral infections, such as herpes zoster. Patients with positive hepatitis screening were excluded from clinical studies. Monitor patients closely for signs of infection during treatment. If serious infection occurs, withhold therapy and institute appropriate treatment, until the infection has resolved. Caution is advised in patients with latent viral infections.

References (1)
  1. (2025) "Product Information. Imaavy (nipocalimab)." Janssen Biotech, Inc.
Moderate

Nipocalimab (applies to nipocalimab) liver and renal impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease, Renal Dysfunction

Nipocalimab has not been studied in patients with severe liver and renal impairment.

References (1)
  1. (2025) "Product Information. Imaavy (nipocalimab)." Janssen Biotech, Inc.

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Nipocalimab drug interactions

There are 297 drug interactions with nipocalimab.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.