Zurnai Disease Interactions
There is 1 disease interaction with Zurnai (nalmefene).
Opiate antagonists (applies to Zurnai) hepatic/renal dysfunction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Opiate antagonists are metabolized by the liver (naltrexone to an active metabolite) and eliminated by the kidney. Hepatic and renal impairment may reduce the metabolism and clearance of opiate antagonists. Dosage adjustment for single dose administration is not necessary, however, repeated doses in patients with hepatic and/or renal dysfunction may require adjustment.
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Zurnai drug interactions
There are 6 drug interactions with Zurnai (nalmefene).
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More about Zurnai (nalmefene)
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- During pregnancy
- FDA approval history
- Drug class: antidotes
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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