Ismotic PB Disease Interactions
There are 2 disease interactions with Ismotic PB (isosorbide).
Osmotic diuretics (applies to Ismotic PB) fluid overload
Major Potential Hazard, High plausibility. Applicable conditions: Congestive Heart Failure, Dehydration, Pulmonary Edema, Anuria
The use of osmotic diuretics is contraindicated in patients with anuria, severe dehydration, pulmonary edema, or severe cardiac decompensation. An increase in the tonicity of the blood may occur in these patients that could exacerbate these conditions.
Osmotic diuretics (applies to Ismotic PB) hyperosmolar effects
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Psychosis, Liver Disease, Diabetes Mellitus, Renal Dysfunction
The use of osmotic diuretics is associated with an increase in blood tonicity. Osmotic diuretics should be administered cautiously in patients with confused mental states, diabetes, congestive heart failure, severe dehydration, and cardiac, renal, or hepatic disease.
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Ismotic PB drug interactions
There are 121 drug interactions with Ismotic PB (isosorbide).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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