Isoproterenol Disease Interactions
There are 3 disease interactions with isoproterenol.
Isopreterenol (applies to isoproterenol) tachyarrhythmias
Major Potential Hazard, Moderate plausibility. Applicable conditions: Angina Pectoris
The use of isoproterenol is contraindicated in patients with tachyarrhythmias; tachycardia or heart block caused by digitalis intoxication; ventricular arrhythmias which require inotropic therapy; and angina pectoris.
Sympathomimetics (applies to isoproterenol) dehydration
Major Potential Hazard, High plausibility.
The use of sympathomimetic amines has been infrequently associated with significant hypotension especially in dehydrated patients secondary to the drug's beta-2 mediated vasodilation. Hypovolemia should be corrected, if possible, before administering sympathomimetic amines. Blood pressure and ECG should be monitored at regular intervals. Monitoring of cardiac output and pulmonary wedge pressure may also be desired.
Sympathomimetics (applies to isoproterenol) acidosis
Moderate Potential Hazard, High plausibility.
Acidosis, hypoxia, and hypercapnia may reduce the effectiveness of sympathomimetic amines in raising blood pressure. These conditions should be corrected before initiating therapy with sympathomimetic amines, if possible. Monitoring the patients acid-base balance, carbon dioxide levels, and oxygen saturation is recommended.
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Isoproterenol drug interactions
There are 399 drug interactions with isoproterenol.
Isoproterenol alcohol/food interactions
There is 1 alcohol/food interaction with isoproterenol.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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