Imetelstat Disease Interactions
There is 1 disease interaction with imetelstat.
Moderate
Imetelstat (applies to imetelstat) renal/hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease, Renal Dysfunction
Imetelstat has not been studied in patients with severe renal impairment or end-stage renal disease, or in patients with severe hepatic impairment. No clinically significant differences in exposure to imetelstat were observed in patients with mild to moderate renal or hepatic impairment.
References (1)
- (2024) "Product Information. Rytelo (imetelstat)." Geron Corporation
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Imetelstat drug interactions
There are 188 drug interactions with imetelstat.
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- Drug class: miscellaneous antineoplastics
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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