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Hydroxyethyl starch Disease Interactions

There are 5 disease interactions with hydroxyethyl starch:

Major

Hydroxyethyl starch (applies to hydroxyethyl starch) coagulation disorders

Major Potential Hazard, Moderate plausibility. Applicable conditions: Coagulation Defect, Intracranial Hemorrhage

Do not use hydroxyethyl starch products with preexisting coagulation or bleeding disorders, including those patients with intracranial bleeding.

Major

Hydroxyethyl starch (applies to hydroxyethyl starch) liver dysfunction

Major Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Do not use hydroxyethyl starch products in patients with severe liver disease.

Major

Hydroxyethyl starch (applies to hydroxyethyl starch) renal disease

Major Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

Do not use hydroxyethyl starch products in patients with renal failure with oliguria or anuria not related to hypovolemia, including those patients receiving dialysis treatment.

Major

Hydroxyethyl starch (applies to hydroxyethyl starch) sepsis

Major Potential Hazard, Moderate plausibility.

Do not use hydroxyethyl starch products in critically ill adult patients, including patients with sepsis, due to increased risk of mortality and renal replacement therapy.

Major

Hydroxyethyl starch (applies to hydroxyethyl starch) volume overload

Major Potential Hazard, Moderate plausibility. Applicable conditions: Hypernatremia

Do not use hydroxyethyl starch products with severe hypernatremia or severe hyperchloremia and in clinical conditions with volume overload.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.