Voluven Disease Interactions
There are 5 disease interactions with Voluven (hydroxyethyl starch).
Hydroxyethyl starch (applies to Voluven) coagulation disorders
Major Potential Hazard, Moderate plausibility. Applicable conditions: Coagulation Defect, Intracranial Hemorrhage
Do not use hydroxyethyl starch products with preexisting coagulation or bleeding disorders, including those patients with intracranial bleeding.
References (1)
- (2013) "Product Information. Voluven (hydroxyethyl starch)." Hospira Inc
Hydroxyethyl starch (applies to Voluven) liver dysfunction
Major Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Do not use hydroxyethyl starch products in patients with severe liver disease.
References (1)
- (2013) "Product Information. Voluven (hydroxyethyl starch)." Hospira Inc
Hydroxyethyl starch (applies to Voluven) renal disease
Major Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Do not use hydroxyethyl starch products in patients with renal failure with oliguria or anuria not related to hypovolemia, including those patients receiving dialysis treatment.
References (1)
- (2013) "Product Information. Voluven (hydroxyethyl starch)." Hospira Inc
Hydroxyethyl starch (applies to Voluven) sepsis
Major Potential Hazard, Moderate plausibility.
Do not use hydroxyethyl starch products in critically ill adult patients, including patients with sepsis, due to increased risk of mortality and renal replacement therapy.
References (1)
- (2013) "Product Information. Voluven (hydroxyethyl starch)." Hospira Inc
Hydroxyethyl starch (applies to Voluven) volume overload
Major Potential Hazard, Moderate plausibility. Applicable conditions: Hypernatremia
Do not use hydroxyethyl starch products with severe hypernatremia or severe hyperchloremia and in clinical conditions with volume overload.
References (1)
- (2013) "Product Information. Voluven (hydroxyethyl starch)." Hospira Inc
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- Drug class: plasma expanders
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.