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Voluven Side Effects

Generic name: hydroxyethyl starch

Medically reviewed by Drugs.com. Last updated on March 18, 2021.

Note: This document contains side effect information about hydroxyethyl starch. Some of the dosage forms listed on this page may not apply to the brand name Voluven.

For the Consumer

Applies to hydroxyethyl starch: parenteral injection

Warning

  • Increased mortality and/or severe renal injury requiring renal replacement therapy reported in critically ill adults, including those with sepsis.1 104 Avoid use in such patients.1 104 (See Contraindications and also see Increased Mortality and Severe Renal Injury under Cautions.)

Side effects include:

Pruritus, increased serum amylase concentrations, hemodilution (resulting in decreased concentrations of coagulation factors, other plasma proteins, and hematocrit).

For Healthcare Professionals

Applies to hydroxyethyl starch: intravenous solution

Cardiovascular

Postmarketing reports: Hypotension/shock/circulatory collapse[Ref]

Hematologic

Common (1% to 10%): Decreased hematocrit

Rare (less than 0.1%): Coagulation disorders beyond dilution effects[Ref]

Hypersensitivity

Rare (less than 0.1%): Anaphylactic/anaphylactoid/hypersensitivity reactions (e.g., hypersensitivity, mild influenza-like symptoms, bradycardia, tachycardia, bronchospasm, noncardiac pulmonary edema)[Ref]

Metabolic

Common (1% to 10%): Decreased plasma proteins[Ref]

Gastrointestinal

Common (1% to 10%): Elevation of serum amylase, interference with the diagnosis of pancreatitis[Ref]

References

1. Cerner Multum, Inc. "Australian Product Information." O 0

2. "Product Information. Voluven (hydroxyethyl starch)." Hospira Inc, Lake Forest, IL.

More about Voluven (hydroxyethyl starch)

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.