Voluven Dosage

Adult Dose

Up to 50 mL of Voluven ® per kg of body weight per day (equivalent to 3 g hydroxyethyl starch and 7.7 mEq sodium per kg of body weight). This dose is equivalent to 3500 mL of Voluven ® for a 70 kg patient.

Pediatric Dose

The dosage in children should be adapted to the individual patient colloid needs, taking into account the disease state, as well as the hemodynamic and hydration status.

In 41 newborns to infants (< 2 years), a mean dose of 16 ± 9 mL/kg was administered. In 31 children from 2 to 12 years of age a mean dose of 36 ± 11 mL/kg was administered. The dose in adolescents > 12 is the same as the adult dose. [see Pediatric Use (8.4)]

Directions for Use of Voluven

1. Do not remove the freeflex ® IV container from its overwrap until immediately before use.
2. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
3. Do not administer unless the solution is clear, free from particles and the freeflex® IV container is undamaged.
4. Voluven ® should be used immediately after insertion of the administration set.
5. Do not vent.
6. If administered by pressure infusion, air should be withdrawn or expelled from the bag through the medication/administration port prior to infusion.
7. Discontinue the infusion if an adverse reaction occurs.
8. It is recommended that administration sets be changed at least once every 24 hours.
9. For single use only. Discard unused portion.