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Magnevist (gadopentetate dimeglumine) Disease Interactions

There are 2 disease interactions with Magnevist (gadopentetate dimeglumine):

Major

Gadopentetate dimeglumine (Includes Magnevist) ↔ asthma/allergies

Severe Potential Hazard, Moderate plausibility. Applies to: Asthma, Allergies

Anaphylactoid and anaphylactic reactions with cardiovascular, respiratory and/or cutaneous manifestations rarely resulting in death have occurred when using gadopentetate dimeglumine. The risk of hypersensitivity reactions is higher in patients with a history of reaction to contrast media, bronchial asthma, or allergic disorders. Hypersensitivity reactions can occur with or without prior exposure to gadolinium- based contrast agents.

Major

GBCAs (Includes Magnevist) ↔ renal impairment

Severe Potential Hazard, Moderate plausibility. Applies to: Renal Dysfunction, Hypertension, Diabetes Mellitus

Gadolinium- based contrast agents (GBCAs) such as gadopentetate dimeglumine, gadoteridol and gadodiamide are contraindicated in patients with chronic, severe kidney disease (glomerular filtration rate, GFR < 30 mL/min), or acute kidney injury. GBCAs increase the risk for nephrogenic systemic fibrosis (NSF) among patients with impaired elimination of the drugs. Their use should be avoided in these patients unless the diagnostic information is essential and not available with non- contrasted MRI or other modalities. NSF may result in fatal or debilitating fibrosis affecting the skin, muscle and internal organs. Caution is advised in patients at risk for chronically reduced renal function (age >60 years, hypertension or diabetes). Always estimate the glomerular filtration rate (GFR) through laboratory testing.

Magnevist (gadopentetate dimeglumine) drug interactions

There are 64 drug interactions with Magnevist (gadopentetate dimeglumine)

Magnevist (gadopentetate dimeglumine) alcohol/food interactions

There is 1 alcohol/food interaction with Magnevist (gadopentetate dimeglumine)

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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