Lytgobi Disease Interactions
There are 2 disease interactions with Lytgobi (futibatinib).
Futibatinib (applies to Lytgobi) hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
The pharmacokinetics of futibatinib has not been studied in patients with moderate or severe hepatic impairment (total bilirubin greater than 1.5 x ULN and any AST).
Futibatinib (applies to Lytgobi) renal dysfunction
Moderate Potential Hazard, Moderate plausibility.
The pharmacokinetics of futibatinib has not been studied in patients with severe renal impairment (CrCl 15 to 29 mL/min), renal dialysis in end-stage renal disease (CrCl less than 15 mL/min).
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Lytgobi drug interactions
There are 179 drug interactions with Lytgobi (futibatinib).
Lytgobi alcohol/food interactions
There is 1 alcohol/food interaction with Lytgobi (futibatinib).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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