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Xiaflex Disease Interactions

There is 1 disease interaction with Xiaflex (collagenase clostridium histolyticum).

Major

Collagenase clostridium histolyticum (applies to Xiaflex) coagulation disorders

Major Potential Hazard, Moderate plausibility. Applicable conditions: Coagulation Defect

Collagenase clostridium histolyticum for injection should be avoided in patients with coagulation disorders, including those receiving concomitant anticoagulant medications, other than low-dose aspirin within seven days prior to therapy administration. Care should be exercised if collagenase clostridium histolyticum for injection is used in these patients.

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Xiaflex drug interactions

There are 55 drug interactions with Xiaflex (collagenase clostridium histolyticum).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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