Inqovi Disease Interactions
There are 3 disease interactions with Inqovi (cedazuridine / decitabine).
Decitabine (applies to Inqovi) liver impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
There are no data on the use of decitabine in patients with hepatic dysfunction. Decitabine should be used with caution in these patients.
References (1)
- (2017) "Product Information. Decitabine (decitabine)." Accord Healthcare Inc
Decitabine (applies to Inqovi) hematological toxicity
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Thrombocytopenia, Neutropenia
Treatment with decitabine is associated with neutropenia and thrombocytopenia. It is recommended to consider the need for early institution of growth factors and/or antimicrobial agents for the prevention or treatment of infections in patients with myelodysplastic syndromes (MDS). Complete blood and platelet counts should be performed as needed to monitor response and toxicity, but at a minimum, before each dosing cycle. After administration of the recommended dosage for the first cycle, treatment for subsequent cycles should be adjusted according to manufacturer recommendations. Myelosuppression and worsening neutropenia may occur more frequently in the first or second treatment cycles and may not necessarily indicate progression of underlying MDS. Closely monitor patients at risk for hematological toxicities.
References (1)
- (2017) "Product Information. Decitabine (decitabine)." Accord Healthcare Inc
Decitabine (applies to Inqovi) renal dysfunction
Moderate Potential Hazard, Moderate plausibility.
There are no data on the use of decitabine in patients with renal dysfunction. Decitabine should be used with caution in these patients.
References (1)
- (2017) "Product Information. Decitabine (decitabine)." Accord Healthcare Inc
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Inqovi drug interactions
There are 227 drug interactions with Inqovi (cedazuridine / decitabine).
Inqovi alcohol/food interactions
There is 1 alcohol/food interaction with Inqovi (cedazuridine / decitabine).
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Decitabine
Decitabine systemic is used for acute myeloid leukemia, myelodysplastic syndrome
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Ivosidenib systemic is used for acute myeloid leukemia, biliary tract tumor, myelodysplastic syndrome
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.