Medically reviewed by Drugs.com. Last updated on Nov 19, 2022.
Uses for Prehevbrio
Hepatitis B vaccine is used to prevent infection caused by all known subtypes of the hepatitis B virus.
This vaccine is to be given by or under the direct supervision of your doctor.
Before using Prehevbrio
In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of hepatitis B vaccine in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hepatitis B vaccine in the elderly.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially:
- Allergy to yeast—Heplisav-B® should not be used in patients with this condition.
- Hepatitis B infection, active or unrecognized or
- Weak immune system—May decrease the effect of the vaccine and the body's response to it.
Proper use of Prehevbrio
A nurse or other trained health professional will give you this medicine. It is given as a shot into one of your muscles, usually in the deltoid (upper arm).
Prehevbrio™ is given in 3 doses. The first 2 doses are given at least 1 month apart. The third dose is given at least 6 months after the first dose. Heplisav-B® is given in 2 doses, at least 1 month apart. To get the best possible protection against infection with the HBV virus, you should complete your vaccine dosing schedule.
Precautions while using Prehevbrio
It is important that your doctor check your progress to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.
This vaccine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, a fast heartbeat, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after receiving the vaccine.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results..
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Side Effects of Prehevbrio
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
- Chest pain or discomfort
- inability to move the arms and legs
- pain or discomfort in the arms, jaw, back, or neck
- sudden numbness and weakness in the arms and legs
Incidence not known
- Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- chest tightness
- difficulty swallowing
- fast heartbeat
- hives, itching, skin rash
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- stomach pain
- trouble breathing
- unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Difficulty in moving
- general feeling of discomfort or illness
- joint pain
- muscle aches, cramps, pains, or stiffness
- pain or tenderness at the injection site
- swollen joints
- redness or swelling at the injection site
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
More about PreHevbrio (hepatitis b adult vaccine)
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