Generic Name: diatrizoate (dye-a-trye-ZOE-ate MEG-loo-meen)
Medically reviewed by Drugs.com. Last updated on Sep 27, 2020.
Commonly used brand name(s)
In the U.S.
- Hypaque Meglumine
Available Dosage Forms:
Therapeutic Class: Radiological Ionic Contrast Media
Uses for diatrizoate
Diatrizoate meglumine injection is used to help diagnose or find problems in the urinary bladder. It is a radiopaque contrast agent. Contrast agents are used to create a clear picture of the different parts of the body during certain medical procedures, such as retrograde cystourethrography.
Diatrizoate is to be used only by or under the direct supervision of a doctor.
Before using diatrizoate
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For diatrizoate, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to diatrizoate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
No information is available on the relationship of age to the effects of diatrizoate meglumine injection in the pediatric population. Safety and efficacy have not been established.
No information is available on the relationship of age to the effects of diatrizoate meglumine injection in geriatric patients.
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving diatrizoate, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using diatrizoate with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of diatrizoate. Make sure you tell your doctor if you have any other medical problems, especially:
- Allergy to iodine or other contrast agents, or history of or
- Asthma, or history of—Use with caution. May increase risk for more serious side effects.
- Urinary tract infection—Use with caution. May make this condition worse.
Proper use of diatrizoate
A doctor or other trained health professional will give you diatrizoate in a hospital. Diatrizoate is given through a needle placed in one of your veins.
Your doctor may give you a laxative the night before the test, and may recommend a low residue diet the day before the procedure.
Precautions while using diatrizoate
Your doctor will check your progress closely while you are receiving diatrizoate. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.
Severe reactions may occur while you are receiving diatrizoate. Tell your doctor if you have seizures, trouble breathing, or tightness in the chest after receiving diatrizoate.
Before you have any medical tests, tell the medical doctor in charge that you are receiving diatrizoate. The results of some tests may be affected by diatrizoate.
Diatrizoate side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Incidence not known
- Blood in the urine
- decrease in the amount of urine
- difficulty with swallowing
- fast heartbeat
- hives, itching, or rash
- not able to pass urine
- pain or burning while urinating
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- shortness of breath
- tightness in the chest
- unusual tiredness or weakness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about diatrizoate
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Drug class: ionic iodinated contrast media
- FDA Alerts (1)