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carbachol (Ophthalmic route)
Commonly used brand name(s)
In the U.S.
- Isopto Carbachol
Available Dosage Forms:
Therapeutic Class: Direct Acting Miotic
Pharmacologic Class: Cholinergic
Uses For carbachol
Carbachol is used in the eye to treat glaucoma. Sometimes it is also used in eye surgery.
carbachol is available only with your doctor's prescription.
Before Using carbachol
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For carbachol, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to carbachol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Although there is no specific information comparing use of carbachol in children with use in other age groups, carbachol is not expected to cause different side effects or problems in children than it does in adults.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of carbachol in the elderly with use in other age groups, carbachol is not expected to cause different side effects or problems in older people than it does in younger adults.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of carbachol. Make sure you tell your doctor if you have any other medical problems, especially:
- Asthma or
- Eye problems (other) or
- Heart disease or
- Overactive thyroid or
- Parkinson's disease or
- Stomach ulcer or other stomach problems or
- Urinary tract blockage—Carbachol may make the condition worse
Proper Use of carbachol
Use carbachol only as directed. Do not use more of it and do not use it more often than your doctor ordered. To do so may increase the chance of too much medicine being absorbed into the body and the chance of side effects.
- First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed and apply pressure to the inner corner of the eye with your finger for 1 or 2 minutes to allow the medicine to be absorbed by the eye.
- Immediately after using the eye drops, wash your hands to remove any medicine that may be on them.
- To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.
The dose of carbachol will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of carbachol. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For glaucoma:
- For ophthalmic solution (eye drops) dosage form:
- Adults and children—Use one drop in the eye one to three times a day.
- For ophthalmic solution (eye drops) dosage form:
- For use during surgery:
- For intraocular solution dosage form:
- Adults and children—Up to 0.5 milliliter (mL), used in the eye during surgery.
- For intraocular solution dosage form:
If you miss a dose of carbachol, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Precautions While Using carbachol
Your doctor should check your eye pressure at regular visits.
After you apply carbachol to your eyes, your pupils may become unusually small. This may cause you to see less well at night or in dim light. Be especially careful if you drive, use machines, or do anything else at night or in dim light that could be dangerous if you are not able to see well.
Also, for a short time after you apply carbachol, your vision may be blurred or there may be a change in your near or distance vision. Make sure your vision is clear before you drive, use machines, or do anything else that could be dangerous if you are not able to see well.
carbachol Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:Rare
- Veil or curtain appearing across part of vision
- Diarrhea, stomach cramps or pain, or vomiting
- flushing or redness of face
- frequent urge to urinate
- increased sweating
- irregular heartbeat
- shortness of breath, wheezing, or tightness in chest
- unusual tiredness or weakness
- watering of mouth
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Blurred vision or change in near or distance vision
- eye pain
- stinging or burning of the eye
- irritation or redness of eyes
- twitching of eyelids
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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More about carbachol ophthalmic
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
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- Drug class: ophthalmic glaucoma agents