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Medications for Systemic Sclerosis-Associated Interstitial Lung Disease

Other names: Scleroderma-Associated ILD; SSc-ILD

About Systemic Sclerosis-Associated Interstitial Lung Disease: 

Systemic sclerosis is auto immune rheumatic disorder which is caused by an overproduction of collagen and proteins in parts of the body which results in scarring in joints, skin, blood vessels and other organs.

One of the major complications of systemic sclerosis is interstitial lung disease which occurs when sclerosis affects tissue and space around the air sacs of the lungs.  This causes scarring and inflammation of the interstitial space and results in breathing difficulties, problems with oxygen transfer in the blood and coughing issues.


Early diagnosis which outlines the severity or stage of the disease is important so that treatment can be started to help stop disease progression, to achieve the best possible prognosis.

Drugs Used to Treat Systemic Sclerosis-Associated Interstitial Lung Disease

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Activity
nintedanib D N Add review
0.0

Generic name: nintedanib systemic

Brand name:  Ofev

Drug class: multikinase inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Ofev D N Add review
0.0

Generic name: nintedanib systemic

Drug class: multikinase inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Learn more about Systemic Sclerosis-Associated Interstitial Lung Disease

IBM Watson Micromedex

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.