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Medications for Respiratory Failure

About Respiratory Failure:  Respiratory acidosis occurs when the lungs cannot remove all of the carbon dioxide (a normal by-product of metabolism) produced by the body. This causes a disturbance of the acid-base balance in which body fluids become excessively acidic.

Respiratory acidosis can be a consequence of any lung disease that prevents removal of carbon dioxide. Common lung diseases that lead to respiratory acidosis include: chronic obstructive pulmonary disease (COPD), severe asthma, or airway obstruction.

Other diseases that may lead to respiratory acidosis include: the obesity hypoventilation syndrome, excessive fatigue of the diaphragm or muscles of the rib cage, or severe deformities of the spine and rib cage (for example, severe scoliosis).

In chronic respiratory acidosis, mild impairment of the lungs' ability to remove carbon dioxide occurs over a long period of time, leading to a stable situation. This is because the kidneys increase their retention of bicarbonate to maintain an acid-base balance in the blood that is almost normal.

In severe cases, the carbon dioxide builds up very quickly, leading to severe disturbances in the acid-base balance of the blood.

Drugs Used to Treat Respiratory Failure

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
nitric oxide C N Add review Rate

Generic name: nitric oxide systemic

Brand name:  INOmax

Drug class: miscellaneous respiratory agents

For consumers: dosage, interactions,

For professionals: AHFS DI Monograph

INOmax C N Add review Rate

Generic name: nitric oxide systemic

Drug class: miscellaneous respiratory agents

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

caffeine / sodium benzoate C N Add review Rate

Generic name: caffeine / sodium benzoate systemic

Drug class: CNS stimulants

For consumers: interactions,

For professionals: AHFS DI Monograph

Topics under Respiratory Failure

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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