Xywav Alternatives Compared
| Xywav | Adderall | Provigil |
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| Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | Adderall (amphetamine / dextroamphetamine) | Provigil (modafinil) |
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Prescription only
Xywav may be used to treat idiopathic hypersomnia in adults or narcolepsy in adults and children aged 7 and older. It contains 92% less sodium than sodium oxybate (Xyrem) because it is made up of a... View more |
Prescription only
Adderall is a combination of four different amphetamine salts and may be used to improve attention, focus, or reduce impulsive behaviors in children over the age of 3 and adults with ADHD. It can... View more |
Prescription only
Prescribed for Shift Work Sleep Disorder, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome. Provigil may also be used for purposes not listed in this medication guide. |
Related suggestions Popular comparisons
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| More about Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | More about Adderall (amphetamine / dextroamphetamine) | More about Provigil (modafinil) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Xywav has an average rating of 7.0 out of 10 from a total of 9 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 22% reported a negative effect. |
Adderall has an average rating of 7.3 out of 10 from a total of 472 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 17% reported a negative effect. |
Provigil has an average rating of 7.4 out of 10 from a total of 164 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: Xywav side effects in more detail. |
See also: Adderall side effects in more detail. |
Common side effects include:
See also: Provigil side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Xywav prices |
View all Adderall prices and generic prices |
View all Provigil prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Other amphetamine / dextroamphetamine brands include: Adderall XR, Mydayis |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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0.66 hours |
34 hours |
15 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 339 drugs are known to interact with Xywav:
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A total of 181 drugs are known to interact with Adderall:
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A total of 458 drugs are known to interact with Provigil:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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July 21, 2020 |
January 19, 1960 |
December 24, 1998 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.