Xywav Alternatives Compared
| Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | Provigil (modafinil) | Modafinil |
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| Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | Provigil (modafinil) | Modafinil |
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Prescription only
Xywav may be used to treat idiopathic hypersomnia in adults or narcolepsy in adults and children aged 7 and older. It contains 92% less sodium than sodium oxybate (Xyrem) because it is made up of a... View more |
Prescription only
Prescribed for Obstructive Sleep Apnea/Hypopnea Syndrome, Narcolepsy, Shift Work Sleep Disorder. Provigil may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Chronic Fatigue Syndrome, ADHD, Fatigue, Depression, Obstructive Sleep Apnea/Hypopnea Syndrome, Narcolepsy, Shift Work Sleep Disorder, Idiopathic Hypersomnia. Modafinil may also be... View more |
Related suggestions Popular comparisons
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| More about Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | More about Provigil (modafinil) | More about Modafinil | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Xywav has an average rating of 8.1 out of 10 from a total of 15 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 13% reported a negative effect. |
Provigil has an average rating of 7.5 out of 10 from a total of 168 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 16% reported a negative effect. |
Modafinil has an average rating of 7.3 out of 10 from a total of 529 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 18% reported a negative effect. |
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Xywav prices |
View all Provigil prices |
View all Modafinil prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
Provigil | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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0.66 hours |
15 hours |
15 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 344 drugs are known to interact with Xywav:
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A total of 510 drugs are known to interact with Provigil:
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A total of 510 drugs are known to interact with Modafinil:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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July 21, 2020 |
December 24, 1998 |
December 24, 1998 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.