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Tussin DM Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Tussin DM Mucinex DM Acetylcysteine
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Tussin DM (dextromethorphan / guaifenesin) Mucinex DM (dextromethorphan / guaifenesin) Acetylcysteine
Prescription and OTC

Prescribed for Expectoration, Cough. Tussin DM may also be used for purposes not listed in this medication guide.

Prescription and OTC

Prescribed for Expectoration, Cough. Mucinex DM may also be used for purposes not listed in this medication guide.

Prescription and OTC

Prescribed for Dietary Supplementation, Expectoration, Acetaminophen Overdose, Diagnostic Bronchograms. acetylcysteine may also be used for purposes not listed in this medication guide.

More about Tussin DM (dextromethorphan / guaifenesin) More about Mucinex DM (dextromethorphan / guaifenesin) More about Acetylcysteine
Ratings & Reviews

Tussin DM has an average rating of 5.0 out of 10 from a total of 1 ratings on Drugs.com. 0% of reviewers reported a positive effect, while 0% reported a negative effect.

Mucinex DM has an average rating of 5.1 out of 10 from a total of 21 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 47% reported a negative effect.

Acetylcysteine has an average rating of 7.7 out of 10 from a total of 42 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 18% reported a negative effect.

View all 1 reviews

View all 21 reviews

View all 42 reviews

Drug Class
Side Effects

See also: Tussin DM side effects in more detail.

See also: Mucinex DM side effects in more detail.

See also: acetylcysteine side effects in more detail.
Generic Availability

N/A

N/A

Lower cost generic
Pricing and Coupons * Prices are without insurance
Quantity 118 mL
Dosage 20 mg-200 mg/10 mL
Per Unit* $0.09 - $0.11
Cost* $10.21 - $12.40

View all Tussin DM prices

Quantity 6 tablet, extended release
Dosage 30 mg-600 mg
Per Unit* $2.52
Cost* $15.10

View all Mucinex DM prices

Quantity 120 mL
Dosage 20%
Per Unit* $1.34 - $1.76
Cost* $160.46 - $211.10

View all acetylcysteine prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Dosage Forms Available
  • Oral liquid
  • Oral tablet, extended release
  • Inhalation solution
  • Intravenous solution
Brand Names
Other dextromethorphan / guaifenesin brands include: Alka-Seltzer Plus Maximum Strength Cough & Chest Congestion PowerFast Fizz, Alka-Seltzer Plus Maximum Strength Cough & Mucus DM, Allfen DM, Altarussin DM, Ambi 1000/55, Amibid DM, Anti-Tuss DM, Aquabid DM, Aquatab DM, Atuss-12 DX, Balminil DM + Expectorant Sugar Free, Benylin Expectorant, Bidex-A, Bidex-DM, Bidex-DMI, Biocotron, Biospec DMX, Broncotron, Brontuss, Chest Congestion Relief DM, Cofex-DM, Congesta DM, Coricidin HBP Chest Congestion & Cough, Coricidin HBP Multi-Symptom Cold (Day), Cough Formula-DM, Creo-Terpin, Delsym Children’s Cough+ Chest Congestion DM, Delsym Cough+ Chest Congestion DM, Dex-Tuss DM, Diabetic Tuss DM, Diabetic Tussin Cough and Chest Congestion DM, Double-Tussin DM, Drituss DM, DuraDEX, DuraDEX Forte, Duraganidin, Duratuss DM, Duratuss DM 12, ExeFen-DM, Extuss LA, Fenesin DM, Fenesin DM IR, Fenex-DM, G Bid DM, G-Tron, G-Zyncof, Gani-Tuss-DM NR, Genatuss DM, GG-DM SR, GG/DM, Giltuss Children's Cough & Chest Congestion, Giltuss Children's Honey Cough & Chest Congestion, Giltuss Diabetic Cough & Cold, Giltuss HBP Cough & Chest Congestion, Giltuss Honey Cough & Chest Congestion, Glycotuss-DM, Guai-Dex, Guaiasorb Cough Medicine, Guaibid DM, Guaifen DM, Guaifen DM NR, Guaifenesin DM, Guaifenesin DM SR, Guaifenex DM, Guiacough DM, Guiadrine DM, Guiadrine DX, Guiat Clear DM, Guiatuss Clear, Guiatuss DM, Guiatussin-DM, HT Tuss DM, Humibid CS, Humibid DM Pediatric, Humigen DM, Hydro-Tuss DM, Mucinex Children's Cough, Mucinex Children's FreeFrom Cough & Mucus, Mucinex Cough & Chest Congestion, Mucinex DM, Mucinex DM Maximum Strength, Mucinex Fast-Max DM Max, Mucosa DM, Mucus Relief Cough, Mucus Relief DM, Pecgen DMX, PediaCare Cough & Congestion, Phlemex, Refenesen Chest Congestion Relief DM, Robafen DM, Robitussin Children' s Cough & Chest Congestion DM, Robitussin Cough + Chest Congestion DM, Robitussin Cough + Chest Congestion DM Maximum Strength, Robitussin Cough + Chest Congestion Sugar-Free DM, Rompe Pecho DM, Safetussin DM, Scot-Tussin Senior, Siltussin DM, Siltussin DM DAS Cough Formula, Siltussin-DM DAS-NA, Siltussin-DM DAS-NA Maximum Strength, Triaminic Cough & Congestion, Tusnel Diabetic, Tussi-Organidin-DM, Tussin DM Max, Vicks DayQuil Cough & Congestion, Vicks DayQuil Mucus Control DM, Vicks Formula 44 Custom Care Chesty Cough, Vicks Nature Fusion Cough & Chest Congestion, Vicks Pediatric Formula 44e Cough & Chest Congestion Relief, Zyncof View more Other dextromethorphan / guaifenesin brands include: Alka-Seltzer Plus Maximum Strength Cough & Chest Congestion PowerFast Fizz, Alka-Seltzer Plus Maximum Strength Cough & Mucus DM, Allfen DM, Altarussin DM, Ambi 1000/55, Amibid DM, Anti-Tuss DM, Aquabid DM, Aquatab DM, Atuss-12 DX, Balminil DM + Expectorant Sugar Free, Benylin Expectorant, Bidex-A, Bidex-DM, Bidex-DMI, Biocotron, Biospec DMX, Broncotron, Brontuss, Chest Congestion Relief DM, Cofex-DM, Congesta DM, Coricidin HBP Chest Congestion & Cough, Coricidin HBP Multi-Symptom Cold (Day), Cough Formula-DM, Creo-Terpin, Delsym Children’s Cough+ Chest Congestion DM, Delsym Cough+ Chest Congestion DM, Dex-Tuss DM, Diabetic Tuss DM, Diabetic Tussin Cough and Chest Congestion DM, Double-Tussin DM, Drituss DM, DuraDEX, DuraDEX Forte, Duraganidin, Duratuss DM, Duratuss DM 12, ExeFen-DM, Extuss LA, Fenesin DM, Fenesin DM IR, Fenex-DM, G Bid DM, G-Tron, G-Zyncof, Gani-Tuss-DM NR, Genatuss DM, GG-DM SR, GG/DM, Giltuss Children's Cough & Chest Congestion, Giltuss Children's Honey Cough & Chest Congestion, Giltuss Diabetic Cough & Cold, Giltuss HBP Cough & Chest Congestion, Giltuss Honey Cough & Chest Congestion, Glycotuss-DM, Guai-Dex, Guaiasorb Cough Medicine, Guaibid DM, Guaifen DM, Guaifen DM NR, Guaifenesin DM, Guaifenesin DM SR, Guaifenex DM, Guiacough DM, Guiadrine DM, Guiadrine DX, Guiat Clear DM, Guiatuss Clear, Guiatuss DM, Guiatussin-DM, HT Tuss DM, Humibid CS, Humibid DM Pediatric, Humigen DM, Hydro-Tuss DM, Mucinex Children's Cough, Mucinex Children's FreeFrom Cough & Mucus, Mucinex Cough & Chest Congestion, Mucinex DM Maximum Strength, Mucinex Fast-Max DM Max, Mucosa DM, Mucus Relief Cough, Mucus Relief DM, Pecgen DMX, PediaCare Cough & Congestion, Phlemex, Refenesen Chest Congestion Relief DM, Robafen DM, Robitussin Children' s Cough & Chest Congestion DM, Robitussin Cough + Chest Congestion DM, Robitussin Cough + Chest Congestion DM Maximum Strength, Robitussin Cough + Chest Congestion Sugar-Free DM, Rompe Pecho DM, Safetussin DM, Scot-Tussin Senior, Siltussin DM, Siltussin DM DAS Cough Formula, Siltussin-DM DAS-NA, Siltussin-DM DAS-NA Maximum Strength, Triaminic Cough & Congestion, Tusnel Diabetic, Tussi-Organidin-DM, Tussin DM, Tussin DM Max, Vicks DayQuil Cough & Congestion, Vicks DayQuil Mucus Control DM, Vicks Formula 44 Custom Care Chesty Cough, Vicks Nature Fusion Cough & Chest Congestion, Vicks Pediatric Formula 44e Cough & Chest Congestion Relief, Zyncof View more Acetadote, Legubeti, N-A-C Sustain, NAC
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

3.6 hours

3.6 hours

6 hours
CSA Schedule ** View glossary of terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
C
Category C Risk cannot be ruled out

See the full pregnancy warnings document.
B
Category B No proven risk in humans

See the full pregnancy warnings document.
Drug Interactions

A total of 361 drugs are known to interact with Tussin DM:

  • 76 major drug interactions (242 brand and generic names)
  • 283 moderate drug interactions (1168 brand and generic names)
  • 2 minor drug interactions (5 brand and generic names)

A total of 361 drugs are known to interact with Mucinex DM:

  • 76 major drug interactions (242 brand and generic names)
  • 283 moderate drug interactions (1168 brand and generic names)
  • 2 minor drug interactions (5 brand and generic names)

A total of 3 drugs are known to interact with acetylcysteine:

  • 1 moderate drug interactions (3 brand and generic names)
  • 2 minor drug interactions (31 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness... View more
  • Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease Interactions

No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
First Approval Date

N/A

April 29, 2004

N/A
WADA Class View World Anti-Doping Agency classifications.

N/A

N/A

N/A
More Information
Patient resources
Professional Resources
Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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