Eculizumab Alternatives Compared
| Eculizumab | Soliris | Ultomiris |
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| Eculizumab | Soliris (eculizumab) | Ultomiris (ravulizumab) |
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Prescription only
Prescribed for Hemolytic Uremic Syndrome, Paroxysmal Nocturnal Hemoglobinuria, Myasthenia Gravis, Neuromyelitis Optica. eculizumab may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Hemolytic Uremic Syndrome, Paroxysmal Nocturnal Hemoglobinuria, Myasthenia Gravis, Neuromyelitis Optica. Soliris may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Myasthenia Gravis, Hemolytic Uremic Syndrome, Paroxysmal Nocturnal Hemoglobinuria. Ultomiris may also be used for purposes not listed in this medication guide. |
Related suggestions Myasthenia Gravis
Paroxysmal Nocturnal Hemoglobinuria
Hemolytic Uremic Syndrome
Popular comparisons
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| More about Eculizumab | More about Soliris (eculizumab) | More about Ultomiris (ravulizumab) | ||||||||||||||||
| Generic Status | ||||||||||||||||||
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No lower-cost generic available |
No lower-cost generic available |
No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||
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Eculizumab has an average rating of 5.0 out of 10 from a total of 2 ratings on Drugs.com. 0% of reviewers reported a positive effect, while 0% reported a negative effect. |
Soliris has an average rating of 5.0 out of 10 from a total of 2 ratings on Drugs.com. 0% of reviewers reported a positive effect, while 0% reported a negative effect. |
Ultomiris has an average rating of 10.0 out of 10 from a total of 3 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
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See also: eculizumab side effects in more detail. |
See also: Soliris side effects in more detail. |
See also: Ultomiris side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Soliris prices |
View all Ultomiris prices |
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| Dosage Form(s) Available | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Soliris |
N/A |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
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354 hours |
354 hours |
1192.8 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 61 drugs are known to interact with eculizumab:
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A total of 61 drugs are known to interact with Soliris:
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A total of 61 drugs are known to interact with Ultomiris:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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N/A |
March 16, 2007 |
December 21, 2018 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.