Comparing Afinitor vs Fluorouracil
Afinitor Remove Afinitor from your drug comparison | Fluorouracil Remove Fluorouracil from your drug comparison |
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Afinitor everolimus Remove Afinitor from your drug comparison | Fluorouracil Remove Fluorouracil from your drug comparison | ||||||||||||||||
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Afinitor (everolimus) is a targeted medicine that may be used to treat various cancers and TSC-associated conditions. It reduces the blood supply to the cancers which slows down their growth and... View more |
Prescribed for Anal Cancer, Breast Cancer, Breast Cancer - Palliative, Cancer, Colorectal Cancer, Cervical Cancer, Pancreatic Cancer, Stomach Cancer. fluorouracil may also be used for purposes not... View more |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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5.6
For Breast Cancer: Although the medication did effectively treat my cancer the side effects were so severe that I decided to discontinue use of the drug and try an alternate treatment. Skin rash started on my hands initially and spread to my entire body causing severe itching and scratching which led to something looking like opened bug bites all over. Severe gum irritation described by my dental hygienist as your gums are flapping in the wind, also red swollen gums which caused me to be unable to eat anything not soft. Lost 10 lbs the first two months. Also projectile vomiting, diahrea and nausea. At three months I found it had made me diabetic and raised my triglycerides to over 500. That's when I opted to stop treatment. |
9.0
For Stomach Cancer: I have been on 5FU for 19 months in combination with Herceptin. My cycle is every two weeks. Initially I also had Oxycelipatin (sp) but I had trouble with neuropathy. My Oncologist expected me to pass in six months to two years. After 19 months of treatment she said, " To be brutally honest I did not expect you to still be here." I am still reasonably healthy, eat well and maintain my weight. My only real problem is that the Herceptin is affecting my heart rhythms. I have the HER2+ protein and my cancer has been found in my Liver. I have had two CT scans wherein I have had a partial response. The rest of my CT scans have shown a stable condition. Scans are conducted every three to four cycles. I am confident that I will make the two year and more timeframe for my life. My Oncologist and Cardiologist are a good team! During my ordeal I have also had to have a Pacemaker installed and may yet have to have it removed and replaced with an ICD. 5FU and Herceptin are working. |
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Drug Class |
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Side Effects |
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Common side effects include: infection, decreased hemoglobin, increased serum glucose, lymphocytopenia, and stomatitis. See the full Afinitor side effects document. |
See the full fluorouracil side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Afinitor prices and generic prices |
View all fluorouracil prices |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Other everolimus brands include: Afinitor Disperz, Zortress |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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35 hours |
0.33 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
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Drug Interactions |
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A total of 415 drugs are known to interact with Afinitor:
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A total of 220 drugs are known to interact with fluorouracil:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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March 30, 2009 |
N/A |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Breast Cancer: I have been taking Afinitor for about 2 weeks. Just feel I cannot continue in with it, feeling like my heart is racing for hours after taking it, it feels close to a panic feeling. No mouth sores(yet) doing the steroid mouth swish as ordered. However, I suddenly have a cluster of large pimple like sores on inner thighs, my skin in general feels very dry. I just cannot deal with sores and am terrified they will become wide spread. I was on Ibrance a year and then it stopped working. The only side effect was fatigue, that I can deal with but sores - no. calling my doctor and telling him the side effects are too much! Give me a med that has fewer serious side effects! I have not taken it long enough to evaluate if it is even being effective. Just no the side effects have begun right away.