Afinitor Compared to Alternatives

For Breast Cancer: Within 7 days of taking Affinitor the fluid in my lung decreased.

For Breast Cancer: Although the medication did effectively treat my cancer the side effects were so severe that I decided to discontinue use of the drug and try an alternate treatment. Skin rash started on my hands initially and spread to my entire body causing severe itching and scratching which led to something looking like opened bug bites all over. Severe gum irritation described by my dental hygienist as your gums are flapping in the wind, also red swollen gums which caused me to be unable to eat anything not soft. Lost 10 lbs the first two months. Also projectile vomiting, diahrea and nausea. At three months I found it had made me diabetic and raised my triglycerides to over 500. That's when I opted to stop treatment.

For Breast Cancer: I have been in tamoxifen for 5 months now and it truly is difficult to isolate the side effects of the drug alone due to the fact that I was peri menopausal prior to being diagnosed with Stage 2 breast cancer with micro metastasis in one lymph node. I am 52 years old. My primary complaint is insomnia. I have become a light sleeper, waking up 10-20 each night. While I am able to fall asleep again, I never feel as though I have had a deep, restful sleep. I take my tamoxifen in the morning after I brush my teeth. A year post diagnosis which included surgery (partial mastectomy), chemotherapy, 25 rounds of radiation and now tamoxifen, I have endeavoured to train for an Iroman race in August. I am getting stronger every day

For Breast Cancer: I have been on Tamoxifen for 10months now..I have had hot flashes, night sweats, mood swings, heavy menstrual bleeding, discharge, headaches and now back pain. But I want to decrease my chance of possibly getting invasive Breast Cancer or DCIS in my other breast..so will continue to take it.

For Breast Cancer: I had a partial mastectomy, nineteen rounds of radiation from April till end of September. I am just over three years on anastrozole. Last year I woke up and the pain in my knees and legs was so sudden and severe, I could barely walk. I'm still losing my hair, am itchy, two teeth broke, weight gain, especially around my middle, where I never gained weight. Sore joints, hands, neck, back. I started feeling a little better and began practising yoga again. This was helping until my head went completely spacey. The foggy brain and groping for words, I was getting used to, but this is a spacey head. When you lie down, you grab for something to hold on to...loss of sleep also. A lot of doctors just ignore some of these symptoms, but go on any site regarding this and so many women are experiencing these symptoms. Anyone else going through this?

For Breast Cancer: I have ductal carcinoma in situ (DCIS) at 70 yrs old. Was told the anastrozole would affect legs and possibly cause osteoporosis. I am one year into it and have 4 more to go. My leg pain (especially lower - like shin splints) keep me up at night. Better when standing. Lying down in supine position seems to trigger it. Hands are weak, but until after reading these comments I had no idea this may be the cause for that as well. Having hard time holding onto things. I seem to be a little forgetful, but that could just be my age. I'm sharing all unusual feelings as it may help someone else relate as it did me after reading some of these. I'm afraid to take tamoxifen as it is known to cause vaginal bleeding. Don't need that! Now Dr. says to try letrozole if I really can't deal with the pain. Being 70, I need my legs to be in good working order - the grass isn't always greener, but I think I'll give it a try.