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Regorafenib and Loss Of Appetite: What Users Say

Brand names: Stivarga

Loss of appetite: mentioned by 4 users (28.6%)

Based on user experiences from 14 Regorafenib reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 28.6%
loss of appetite 28.6%
weight loss 21.4%

Reviews for Regorafenib

Commonly mentioned side effects
  • Can...
  • July 20, 2017

For Colorectal Cancer "I am writing this as a data point for those who may be considering this drug. My mother was recently put on this, and it was literally the worst drug she's ever taken in her 6-year journey battling cancer. I read the reviews and begged her not to take it, but she went through with it anyway. The drug caused her to be lethargic to the point where she could not move. She had a severe loss of appetite, she broke out in hives, she lost a significant amount of weight, and could barely walk or clothe herself. She literally could not function. She took it for two weeks, and by the end of it, she was so incoherent and weak that she collapsed inside of our home. And this was from taking 2 pills one week and 3 pills the next."

2 / 10
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72 Report
  • Anonymous
  • Taken for 1 to 6 months
  • August 26, 2020

For Colorectal Cancer "My husband is going to begin his 3rd month of this med Stivarga on 8/29/20. Dosage is 4 pills a day/160 mg. He takes it on a cycle of 3 weeks on & 1 week off. His side effects have gotten progressively worse as the 3-week cycle progresses until the point of he can barely function due to lethargy, severe weight loss (he lost 8 lbs in a month) & loss of appetite. Currently, he is off medication for 1 week and each day his appetite & energy gets better. I dread 8/29/20 when I know his side effects are going to return. So far, we don't know if this drug is effective on his metastatic stage 4 colon cancer because his doctor hasn't ordered a CT scan yet. Written 8/26/20."

5 / 10
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23 Report
  • Tse...
  • March 19, 2022

For Colorectal Cancer "My husband took this med, 4 tabs for 3 weeks and 1 week off. Due to severe side effects, down to 3 tabs for 3 weeks and one week off. But now, due to severe side effects, extreme lethargy in bed for the last 3 weeks. He went to emergency twice due to bleeding, but not sure from where, waiting for endoscopy approval. Loss of appetite, lost so much weight. Does not look like the same person he was a month before. Please don't give this to your loved one for any reason. This is pure poison, which is so bad for cancer patients. I am so sad, 2022, and drug companies and doctors giving this poison to innocent and sick people. This is pure torture. Please don't give this to your loved one."

1 / 10
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17 Report
  • Nom...
  • Taken for 1 to 6 months
  • August 20, 2022

For Colorectal Cancer "In late March 2022, to make a long story short, my oncologist suggested I try Stivarga as another line of treatment. I have colon cancer, but it wasn’t debilitating until I started Stivarga. I was fully employed until May 2021 when I made the decision to stop working to give my health more attention as needed for cancer care. I exercised at least 5 out of 7 days a week, running, long walks, weights, etc. Well, my Stivarga was delivered by UPS in February 2022, and my oncologist prescribed it to start 2 pills a day week one, then 3 pills a day week two, and finally 4 pills a day from then on. Three weeks on and the fourth week off. I had extreme lethargy and zero appetite. I lost 30 lbs in 4 months. I would sleep for 8-10 hours at night, get up and have my low-fat breakfast so pills can be taken, and actually fall asleep with my cup of coffee in my hands. I’d lay down on the sofa and fall asleep again. The 3rd week of June 2022, I quit taking it and told my oncologist no more."

1 / 10
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11 Report

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