Ospemifene for Dyspareunia User Reviews

• Mar...
• Taken for 1 to 6 months
• April 9, 2015

"This medication started working immediately. Within three days, more moisture. Within the next week, my interest in sex returned and I felt a major decrease in pain. I have been using this medication for 5 months now. Am I completely discomfort free? No. However, with the use of a lubricant like coconut oil (the best I've used) or olive oil (second best), both of which are the most like the body's natural moisture and some modifications in position or speed, this medicine has been a miracle for us. Unlike when we were young, it takes more preparation to be physically ready for intercourse, but we've adapted to those changes. I was/am frightened by the potential side effects. The only drawback for me at this point is an increase in night sweats."

• Juj...
• March 5, 2016

"Sex had become so painful and no matter how much lubricant we used, it just did not work. I dreaded sex and had no desire for it. I suffered for 3 years. On my yearly exam with my gynecologist, she told me I was fire engine red down there, so we discussed Osphena. After three days, I noticed a difference. This is hard to share, but I now feel like I am 30 down there (I am 50). I have sexual urges again. I get lubrication just thinking about sex. My husband is thrilled and said it's like before my menopause. I have nothing bad to say about this. It has given me back my sex life. I must admit I am worried about the side effects that can happen, so I want to keep check-ups regularly. I have heard some gain weight on this. I have not."

• Tra...
• Taken for 1 to 6 months
• July 21, 2016

"I am a 58-year-old woman who entered menopause at 40. I have dealt with severe dyspareunia, vaginal atrophy, and dryness for years now. I have tried everything on the market. My doctor has given me prescriptions for creams, HRT, and suppositories, none of which gave me anything but temporary relief. Intercourse has been extremely painful and difficult. After talking to my doctor at length, I decided to try it. I noticed a significant difference within 5 days. I was nearly pain-free during intercourse! Then the headaches began. A dull, consistent ache in the right side of my head. There was also intermittent nausea. This medication is a Godsend IF you don't suffer any side effects. Unfortunately, I can no longer take Osphena."

• Anonymous
• Taken for 1 to 6 months
• June 4, 2019

"This drug has renewed my sex life! My husband is thrilled, and I’m pretty darn happy, too! I was getting depressed about how painful sex was and how little of it we were having. Now, it’s like I was 20 years ago!"

• Hap...
• Taken for 2 to 5 years
• October 27, 2017

"I am 65, have taken Osphena for about 2 1/2 years now, no side effects ever noted. How quickly I had positive results after starting this med, I do not remember. I do know that my sexual desire increased, and my poor once-dry vagina now lubricates with even the thought of having intercourse. I make sure I do everything I can to stay healthy, so I can continue this medication and stay sexually active for a long time. My husband is thrilled, too!"

• ger...
• June 7, 2017

"I have always had an active sex life; at about age 59, sex became very painful. Put up with it for several years until I discovered Osphena. It has made life so much better. There is still some discomfort, but that is a minimal price to pay to be intimate with my husband of 45 years. I would highly recommend this drug. :)"

• wil...
• November 10, 2015

"Made a significant positive difference in post-menopause symptoms. However, substantial side effects, worst of which is facial edema with distortion to facial features. Tested this by stopping the med several times to clear it from the system, and when I did this, edema disappeared but reappeared once I resumed the drug. Also, strong hot flashes and sweating. No weight gain."

• Jan...
• Taken for 1 to 6 months
• July 31, 2019

"At first, it was definitely helping with dryness. Then I was wetting my pants all the time, and I got a horrific yeast infection -- took three rounds of medication to fix it. I also felt stressed -- lack of energy and weakness. I didn't realize how bad that had gotten until I went off it. The yeast infection was the final straw. Then, after being off it for a week, ovarian pain began, and I now will need to get this checked off. I went through early menopause (46). I think I have exhausted all options for the pain at this point."

• Ton...
• September 23, 2018

"For years after having a complete hysterectomy at age 45, intercourse was very painful. I have been taking Osphena for three years without any side effects. To me, it is a miracle drug. I had given up on sex, and now I enjoy sex with my husband on a regular basis without worrying about possible side effects. I would rather live a full life with my husband than not having a life at all. Thank you, Osphena."

• slm...
• July 5, 2015

"Just started taking Osphena after fighting with insurance for almost 3 years to allow it to be covered. (cash price $204.00) After 3 days' use, I have noticed an increase of natural vaginal lubricant. I can't wait to start having a sex life again with my husband! Looking forward to the promises and not too worried about the side effects. Thank you, Osphena, for bringing us back to life!"

• She...
• Taken for less than 1 month
• November 23, 2016

"Everyone is obviously so different. My experience wasn't even close to as positive as some of the others have mentioned. Thankfully, I received a physician's sample and did not purchase it. I took about 6 days' worth and noticed increased discharge. After taking it for another 7 days, I woke up with the worst headache. Headaches are very rare for me. Then I noticed some spotting on my underwear. By the evening, I was sweating heavily and just felt horrible. It was then that I decided to look up side effects. I have discontinued taking this medication. It's just not worth the side effects for me. Your mileage will certainly vary."

• Let...
• Taken for 1 to 6 months
• January 1, 2019

"I've been taking Osphena for about 2 months. I've had no side effects up until now, and the pain I was experiencing during sex has subsided a lot. It's not perfect yet, but better than it was. However, suddenly I've developed a yeast infection. I've never had yeast infections - only ones out of the blue, only after finishing a course of antibiotics. I read that yeast infections can occur when there is an increase in estrogen. So now I am wondering if I need to stop taking Osphena and if it's the reason I have a yeast infection."

• myy...
• July 5, 2018

"I've been taking Osphena for 8 months now, and it helped my vaginal dryness, but side effects are hot flashes, slight headache, and gaining weight! To date is my heaviest weight in my entire life. Anyhow, before, I had to pay $0 with my old insurance, but now I have a new insurance, and it's not covering the Osphena. It's so expensive to pay $243 every time I refill. I can't afford it anymore. My ob-gyn said there's no generic for Osphena, and she didn't give me any alternative. :("

• Dan...
• Taken for 1 to 6 months
• September 15, 2016

"I noticed some improvement after a few weeks, but still had some mild discomfort and spotting after intercourse. I have gained weight (about 5 pounds in a 6-week period), I have headaches, I have hot flashes, and some severe leg cramping (not a normal problem even with my line dancing). I am going to discontinue this drug."

• hot...
• Taken for 1 to 2 years
• September 30, 2017

"Osphena came into my life via a rep to the office. I'm a female GP who sees vag complaints daily. I personally had gone through the big pump bottle of lube every few months. Osphena makes me as wet and tight as I was before we married 28 years ago, according to my husband. Much better sex for both of us and no lube needed. Chronic headaches lifelong, no worse."

• Nor...
• Taken for 2 to 5 years
• December 10, 2020

"I've been using Osphena for several years, and it changed my life. I could not have sex after menopause due to severe pain, like broken glass. I've had no side effects, no weight gain or bloating. Some leg cramps are easily handled with Ca/Mg supplement. But in addition, my gyno has me using melted coconut oil on penetration. She said do not use OTC lubricants, as they have ingredients that are drying. I also used a vag dilator for a while, as my muscles were so tight from pain avoidance."

• Eia...
• Taken for 1 to 6 months
• March 27, 2018

"I've been taking Osphena for two months. It has definitely helped with dryness. However, I have constant discharge and have gained 6 lbs. I am not eating more and was the same weight for years. It is crazy. I thought that I would stop gaining and my body would go back to normal, but it hasn't. I'm going off the medicine and trying the Femilift."

• Peg...
• Taken for less than 1 month
• February 28, 2018

"I am 30 years old, this med has been a blessing to my life! After 4 days of taking it, I could feel the difference. I recommend this med to anyone who may be experiencing this issue. I also haven't had any side effects."

• wel...
• Taken for 1 to 6 months
• February 19, 2020

"This product did absolutely nothing for me! I went through five months of pills just waiting for something to happen. But, all I did was fill my body with some type of synthetic drug that had zero impact on my problem. I would never recommend this product."

• GaN...
• Taken for 1 to 6 months
• April 6, 2020

"I've been taking Osphena for 3 months for painful intercourse. My doctor said to give it 3 months, and I did, but sex still hurts, and the side effects are pretty bothersome. Hot flashes, weight gain, bloating, and the worst is the bitchiness. My husband said he'd rather have his sweet wife back. I'm calling the doctor today, but leaning toward stopping it."

• Sue...
• August 28, 2016

"I have experienced a 90% reduction in both vaginal bleeding and painful intercourse. This medication is miraculous. I enjoy sex again!"

• Dol...
• Taken for less than 1 month
• September 5, 2016

"Horrible hot flashes and depression."

• LLP...
• Taken for 1 to 6 months
• April 14, 2019

"I have taken this for 3 months and still have very painful sex, feel like a hot poker. I am discontinuing."

• Mea...
• Taken for 1 to 6 months
• April 23, 2019

"Wish I had started Osphena years ago. Works amazingly."

• Pia...
• Taken for less than 1 month
• June 14, 2018

"I have gained 5 kgs. I am quitting this. I feel bloated."