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Huperzine a User Reviews & Ratings

Huperzine a has an average rating of 8.9 out of 10 from a total of 16 reviews on Drugs.com. 93% of reviewers reported a positive experience, while 0% reported a negative experience.

Condition Avg. Rating Reviews Compare
Myasthenia Gravis  
8.9
16 reviews for Myasthenia Gravis 13 medications
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Reviews for Huperzine a

  • mgcoper
  • February 6, 2010

For Myasthenia Gravis "I have been using this product since I was diagnosed with Myasthenia Gravis 4 years ago. I usually take 200mcg once a day in place of mestinon. Some days I take a second dose in the evening. It does not give me the roller coaster effect that mestinon does. I love the product, it's been a lifesaver. Now, over time, after a couple of months, it becomes a little ineffective. Then I switch to the mestinon for a week or two, and then go back to the Huperzine. It definitely works for me and is not a placebo effect. I can go from barely able to lift a glass of water to doing pushups within about an hour or two, and the effects last 6-8 hours with a gradual decrease in effect, unlike the mestinon, which drops very fast."

9 / 10
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92 Report
  • PLEASE...
  • November 12, 2018

For Myasthenia Gravis "I tried Huperzine A thinking it could be a good natural treatment option. I took one pill daily even though it said to take every 3 to 4 hours, 4 pills a day. Soon, I increased to two pills a day, one hour after taking the second pill, I became deathly ill with a reaction called a cholinergic crisis, which can cause respiratory failure. Huperzine A should be taken with caution! You should start on a low dose and give yourself time for the drug to build up in your system, just like Mestinon. I believe that this drug may very well do everything Mestinon is meant to do (maybe more) for people with Myasthenia Gravis, but there should be more careful dosage instructions on the bottle! So please take this drug slowly, start with a low dose for maybe a month before increasing your dosage, and only do so if necessary. Keep a strict schedule, too much of this drug in your system can cause serious sickness, even death."

6 / 10
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36 Report
  • senio...
  • Taken for 2 to 5 years
  • September 2, 2023

For Myasthenia Gravis "I had taken mestinon for three years with TERRIBLE side effects; 24/7 abdominal pain, night sweats, explosive diarrhea, and nearly every other side effect listed for Mestinon! I hated taking it. I heard about Huperzine A, what did I have to lose? Couldn't be worse than mestinon! I have been taking Huperzine A now for over 3 years. NO SIDE EFFECTS. Unless I'm having a bad MG day, I only take one 200mcg per day, effects lasting for several hours, twice as long as Mestinon, and kicks in twice as fast as well! If I'm having quite a bad MG day, I sometimes take a second dose in the pm. Will NEVER use anything else for MG symptoms again!"

10 / 10
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9 Report
  • Suzi...
  • Taken for less than 1 month
  • December 18, 2018

For Myasthenia Gravis "Could not tolerate Mestaton after one day side effects were intolerable. This Huperzine A gave me a slight headache first 2-3 Days, but I’m amazed I take one 200 mg with breakfast and ALL My Myasthenia Gravis symptoms are now in control. Still on smaller dose of Prendisone but I’m feeling “normal” first time in 5 months. I will not increase dose, may keep 5/7 days to stay balanced....wonderful ."

9 / 10
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19 Report
  • Bama...
  • Taken for less than 1 month
  • April 7, 2023

For Myasthenia Gravis "My MG responded to mestinon only at 120mg dose, which I took 4 times a day at 4-hour intervals. On that dose, I had: 1) overactive bladder from hell - run or trot 10 times most workdays, peeing before I get in the bathroom, must wear diapers daily, the cheaper OAB meds can’t be taken, leave only 2 meds to choose: myrbetric didn't work, Gemtesa’s better at $166/m copay 2) Bowel movements were frequently urgent and interrupting, usually, a muddy consistency and can be diarrhea 3) pupils don’t dilate in the dark - every shadow, under every piece of furniture, and car floorboard is all jet black, I wear headlamps in my house to find things. 4) it wore off dramatically quickly, esp 2:30 pm and 6:30 pm On huperzine A, and on Gemtesa, I can hold a lot of urine now, but still, urgency when I unzip; BMs are less frequent and firmer, my house is notably better lighted, and I get 10 hours benefit so I take a second dose at 4:30 pm. Taking two 200 mcg capsules I get quite weak, 1 is the dose. Much better muscle strength and stamina."

9 / 10
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  • Hip2VP
  • Taken for less than 1 month
  • January 20, 2018

For Myasthenia Gravis "Works very well as a replacement for Mestion. For me, it is slightly less effective in the nasal area but being that MG weakness can come and go in any area, that may have nothing to do with the Huperzine A. 200 mcg lasts me from 6 to 8 hours just as a previous person posted. It also has a much smoother onset and decay than mestinon. I've been using it for about a week. So far so good."

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • August 29, 2023

For Myasthenia Gravis "After taking this for a few weeks, it has made such a difference. I do have asthma and the first few days, it did give me something like an exacerbation. I took my albuterol inhaler more often. I now take it along with NAC which helps a lot with the asthma. I will continue to take it as it helps with my muscle weakness a lot."

8 / 10
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  • Terry
  • January 20, 2021

For Myasthenia Gravis "huperzine helps and love it because it is a natural. When I took standard meds all side effect were too much. This lasts 6 to 8 hr and helps me function normally again. Use 200 mg morning can do second at night of needed..."

8 / 10
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7 Report
  • Huper...
  • Taken for 6 months to 1 year
  • December 10, 2023

For Myasthenia Gravis "I heard about Huperzine A and started taking it last year. I noticed a huge difference. I actually went into remission. I was taking one 200 mcg pill a day. After about eight months, I started to get weak, double vision, and couldn't function on a daily basis. I went to the doctor, and he sent me straight to the hospital. He said I was in a myasthenic crisis. I did IVIG for five days and took mestinon 60 mg every four hours. It seemed to work, but now I'm back at square one with a weak, droopy eyelid. I wanted to start Huperzine A again, but my doctor wants to try me on Vyvart. I hate trying new medicine because I never know how it will affect me. I'm glad to know that Huperzine A is helping others."

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  • ninjaM
  • Taken for less than 1 month
  • May 20, 2024

For Myasthenia Gravis "Two months ago I got diagnosed with Ocular Myasthenia Gravis. I suffered with diplopia and ptosis badly. I couldn't afford medical treatment, so I took alternative affordable supplements. After a thorough research, I came across Huperzine A and only started taking it with Citicoline 250mg a few days ago. The 200mcg wasn't in stock so I've been taking 100mcg twice a day and added a third dose on the second day. I'm totally blown away at how much it alleviated my eyelid's droopiness for several hours in the day and more late in the evening. I think micro dosing is just nice to avoid adverse effects or any imbalance in the long run. I will stay with this regime. Thank God for Huperzine A. I am looking forward to seeing a full remission soon!"

10 / 10
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  • Robert
  • Taken for 1 to 6 months
  • May 22, 2024

For Myasthenia Gravis "I have been taking Huperzine A and DMAE for 6 weeks now. My MG flared up after a surgery to remove my right kidney that had a benign tumor on it. I have been on Mestinon 60 mg 3 times daily as well as Mestinon 180 mg 3 times daily and Cellcept and Soliris IV treatment. I had two Soliris treatments after the surgery, which I have been on for almost two years and it was helping. I had all of the usual side effects from the Mestinon too. After I took the first 200 mcg capsule with the 150 mg capsule of DMAE, within two hours I first noticed my eyelid drooping had stopped. Then about 30 minutes later my hand and leg strength improved. I have upped the Huperzine A to 400 mcg and improved my stamina. I am going to start reducing the Mestinon 180 mg. My doctor has been wanting me to reduce and get off of it, if possible. I should be able to with the Soliris and the Huperzine A & DMAE combo. I have high hopes for it. Wish me luck. Thanks"

10 / 10
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  • Bob
  • Taken for 2 to 5 years
  • July 13, 2024

"I've been using Huperzine A for a couple of years, off and on, before seriously taking it regularly about 6 months ago. It helps with various different issues that come with having Ehlers-Danlos. One of the biggest things that I have noticed with it is that it helps with gastroparesis issues and helps keep my stomach working. In addition to that, I've noticed some improvement with POTS symptoms, mainly helping keep my legs from getting sore (I still use Vittasium regularly as well as midodrine during times of physical activity). I also feel like it helps brain fog a good bit as well, but for this specific use, I can't be certain it's not a placebo effect. I take 100mcg every morning."

9 / 10
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  • HUPAG...
  • Taken for 6 months to 1 year
  • October 22, 2013

For Myasthenia Gravis "HUP A!!!! works just like Mestinon without the side effects!"

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  • MG Su...
  • Taken for 2 to 5 years
  • April 19, 2022

For Myasthenia Gravis "Huperzine and DMAE eventually led to remission. Taking no medication now."

10 / 10
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13 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • August 21, 2021

For Myasthenia Gravis "Agree with other reviews it helps and works with no side effects. Take it 2 or3 times a day..or as needed less....great natural"

9 / 10
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  • Itwor...
  • March 5, 2017

For Myasthenia Gravis "HUP A is natural substitute for mestinon. Loving it"

10 / 10
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17 Report
  • Anonymous
  • Taken for 1 to 6 months
  • October 5, 2024

For Myasthenia Gravis "It worked exactly the same as Mestinon, but lasts for longer."

9 / 10
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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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