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User Reviews for Bupropion / naltrexone

Also known as: Contrave

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Obesity
6.9
   
1,053 reviews 62 medications
Weight Loss
6.5
   
490 reviews 44 medications
Not Listed / Other
6.2
   
9 reviews
Summary of Bupropion/naltrexone reviews 6.8 1,552 reviews

Reviews for Bupropion/naltrexone

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Contrave (bupropion / naltrexone) for Weight Loss: "Went on it in Dec 2017. I noticed mild constipation (didn't have to take anything for it) and sleeplessness if I took the last dose close to bedtime. I also had pretty bad nightmares. Continued my dose and lost 20 pounds in 2 months. Unfortunately didn't get my refill timely (my fault) and had zero withdrawals. Back on it again and notice the exact same things. Some nausea but I try to eat a little something with the pills and that seems to take it away. It works if you let it. Funny to notice how coffee cravings, sugar cravings are totally gone."

   
9.0

sarah (taken for 1 to 6 months) April 13, 2018

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Contrave (bupropion / naltrexone) for Obesity: "I started taking Contrave in Nov. 2017. In the first week I had lost 7 pounds. I had previously (before Contrave) felt irritable all the time. After I started taking the drug, my emotional state seemed to improve. For the first two months sides affects were extreme nausea, constipation, fatigue and dry mouth. All of which I could live with. At my three month follow up visit with my doctor, I had lost 25 pounds. Since then, I have continued to take the drug but the appetite suppression has faded. I feel like I'm struggling to do all the work myself. I go to the gym every day and walk close to three miles. I also struggle to not over eat. I've only lost five pounds in the last two months. My main concern is the irritability has returned ten times stronger. I meet with my doctor again next month. Not sure if I will be continuing the drug."

   
6.0

Pam (taken for 1 to 6 months) April 13, 2018

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Contrave (bupropion / naltrexone) for Obesity: "Be very very careful when taking this medication if you are already depressed. I had to stop taking this med. I already a slight issue with depression and taking contrave made it a whole lot worse. Started thinking things that you should never think of. Felt very lonely and sad."

   
2.0

Shell (taken for less than 1 month) April 12, 2018

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Contrave (bupropion / naltrexone) for Obesity: "I had to pay full price for this medicaton b/c insurance would not pay for it. I spent 500.00. This was as a financial hardship since I am living on social security. However, my weight gain was a serious problem. Throughout the program [3 mos] I lost approx 20 lbs. within a short time I gained it all back again plus another 6 -8 lbs!! I really thought this program would work better than it did. I had used the chantix which had the same possible side effects listed and I had experienced none of them. I haven't smoked in 13 years!! I did not have any side effects with the contrave. I completed the program. the physician would not allow to me to take it for an extended period . Now I am fat and broke. Since chantix was such a success and primarily the same way as your contrave I hoped for better results. "

   
3.0

joni April 12, 2018

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Contrave (bupropion / naltrexone) for Weight Loss: "Started taking it March 1, 2018. Weight: 206lb. As of April 12, down by 24 pounds. It works exactly as described - reducing cravings (at night time, esp. for me) and (as a bonus)has reduced anxiety and other compulsive behaviors. I did modify the dosage - once up to the recommended two tablets 2x daily, I tweaked it to 2 tabs before breakfast, one at 3:30pm, and another at bedtime. Side effects: some weird dreams at first, a little nausea that went away, and some continued grassiness. Definitely worthwhile if it works for you."

   
10

Sonny (taken for 1 to 6 months) April 11, 2018

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Contrave (bupropion / naltrexone) for Weight Loss: "I just started today. I have struggled with weight all my life up and down but once having children its been down hill from there. I'm hoping the side effects aren't to bad for me. I stopped my wellbutrin in order to take this so I'm hoping it being in my system will help. I will update my progress by the week. I just took a month of phentermine it works for a very short term. I lost 9 pounds in a month but I also basically starved myself. I have also gained some of that back so its short term. I just pray this works. Good luck to everyone on this journey of getting healthy."

   
10

Anonymous April 11, 2018

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Contrave (bupropion / naltrexone) for Obesity: "2.5 years ago I had total thyroidectomy and partial para thyroid. I just kept gaining month after month. Tears came to my eyes when after 6 weeks I lost 8 pounds. I love this Med. A life saver. Contrave cuts my appetite and cravings. I can have one cookie but easy to turn down the second. Now craving salad and veggies."

   
10

LuvitNOW April 10, 2018

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Contrave (bupropion / naltrexone) for Weight Loss: "I thought I was going crazy.. The hot flashes, nausea, forgetfulness. It was so bad!!. I was having trouble sleeping, and terrible headaches! I never ever felt any less hungry.. I stopped taking after a month and a half and no results! Not worth $100"

   
1.0

Justina (taken for 1 to 6 months) April 7, 2018

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Contrave (bupropion / naltrexone) for Weight Loss: "I began taking it in Oct of '17 and I experienced zero side effects. It took a month before I felt any change at all. It finally kicked in in Nov. By Christmas I had dropped 14 lbs without even trying. I literally felt like it was my miracle drug. It made me feel like everything was balanced. My sleep and energy. Some weeks I'd lose 2-4 lbs. I rarely felt like snacking. I'd only eat part of a meal when eating out. It was great. However, after a week of poor eating at Christmas I just couldn't seem to get back on track. Now it's April. I haven't lost any more weight. We went to my parents' for Easter last weekend and for some reason I kept skipping the doses. I realized after skipping 3 in a row (unintentionally) that I did not feel any side effects of withdrawal So, with the idea of "if it's not working, don't take it" I just didn't take it again. It will be one week tomorrow that I have been off of it (cold turkey). I plan to start back up after being off of it for a month, maybe 3 weeks."

   
9.0

LG Doppleganger (taken for 1 to 6 months) April 7, 2018

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Contrave (bupropion / naltrexone) for Weight Loss: "I have taken Contrave for almost 1 month. I am female, 5"1 and 21 years old. I cant not express my joy with the successes of this pill. I never realised how much I depended on food. I feel like I was literally addicted. I have had no side effects other then dry mouth. No nausea or headache or anything. My heaviest is 174lb around the 8th of March . Now, April 5, it is 157lb and decreasing FAST and with very little exercise. Not only do I eat less, I make healthier decisions in food choices as well! This pill has given me a new hope for a better, healthier future. This sounds like a planted comment haha! But its honestly great. Worth it."

   
10

GoingDown April 5, 2018

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Contrave (bupropion / naltrexone) for Obesity: "I’m on day 5 now of taking one pill and I just cannot tolerate this medication. I feel high as a kite and awful: very anxious, highly medicated, as if I’m on speed, extremely tense and disoriented. Yes, my appetite is well under control but I feel barely human at this point. I feel like I’ve been hit with a ton of bricks."

   
1.0

Ann (taken for less than 1 month) April 4, 2018

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Contrave (bupropion / naltrexone) for Obesity: "I've been using Contrave for several weeks. I take 3 per day. One in the morning, one around lunch and one after dinner. I tried taking 2 at once and felt stoned so I am doing my own thing. I take it along with prozac and have no negative side effects. What I do notice is that after dinner, I'm done. No more cravings. I have a food addiction so this was perfect for me. No longer eating away my feelings. Two months in and 20 pounds lighter. I have also been using this in conjunction with My Fitness pal app and try to eat only 1100 calories a day. Somedays I'm under and sometimes I'm over my calories. It's not a miracle drug, but it helps me control what I eat and when. Honestly, I don't even think about food after dinner. Hope this was helpful."

   
8.0

Jennyh142 (taken for 1 to 6 months) April 4, 2018

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Contrave (bupropion / naltrexone) for Weight Loss: "I was excited to try Contrave understanding it’s a combination of two drugs that could help with depression & weight loss. The first day I took ONE pill and felt anxiety, sweating & like I was going to explode. Thought maybe it was just because of first day. Second day, again ONE pill and had same symptoms of first day plus it made me feel sick and insecure. Had these side affects for five additional days even though I stopped after pill 2. I want a refund. They should at minimum offer a trial of 10 pills instead of making us buy over $100 worth and have them go to waste."

   
1.0

CMac (taken for less than 1 month) April 4, 2018

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Contrave (bupropion / naltrexone) for Weight Loss: "I got a prescription for Contrave on 3/20/18 and was 216 lbs at the doctors office. Yesterday 3/31/18 when I weighed, the number was 203 lbs. The first day I had some pretty bad nausea, but I took some Bonine that day and with the Contrave the next day. I have not had to take the Bonine anymore and do not have any nausea. My appetite was gone by the second day. I make sure to take a multi-vitamin and only eat small amounts a couple times a day. I hope this continues. I will definitely take 13 pounds in 11 days. I can say "no" to things I really like, but I still would really like to have that cake. :("

   
10

Carol (taken for less than 1 month) April 1, 2018

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Contrave (bupropion / naltrexone) for Weight Loss: "I had some reservations due to the side effects and expense but started 6 weeks ago and am down 13 pounds. This is my first prescription diet pill. It’s not a miracle drug but absolutely helps keep me in check most of the time. I was on the “17 day diet” which is highly effective for me. Then on vacation for 10days and ate and drank whatever I wanted but exercised daily. I lost 2 more pounds! I had minor headache and dizziness first week or so but now is gone and I’m sleeping better than ever."

   
9.0

Sharon March 31, 2018

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Contrave (bupropion / naltrexone) for Obesity: "I took Contrave for four weeks. Once I progressed to two pills a day, it began to give me headaches and the worst dizzy spells ever. I never felt any appetite changes and honestly began to have anxiety issues. I had problems sleeping at night as well. I paid a lot of money for this medicine and it makes me sad that I couldn't take it."

   
2.0

Kern (taken for 1 to 6 months) March 30, 2018

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Contrave (bupropion / naltrexone) for Obesity: "I have been taking Contrave for 5 weeks. I have a knee injury, so my results are purely based on reduced appetite. 9.5 pounds lost. I only had mild nausea the first couple days and it was very tolerable. I had none of the other side effects. I just do not think about food all the time, and if I am not hungry, I'm not interested in food. When I do eat, I enjoy it, but I am able to push it away if I'm not hungry. I consider this a success, and I'm looking forward to next month's weight loss. My doctor is very impressed."

   
9.0

Beth (taken for 1 to 6 months) March 30, 2018

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Contrave (bupropion / naltrexone) for Obesity: "Induced extreme insomia, dry mouth, hot flashes, forgetfulness. Took two weeks recommended dosing. Decided I had to stop for my health."

   
1.0

Meh (taken for less than 1 month) March 27, 2018

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Contrave (bupropion / naltrexone) for Weight Loss: "Beginning week three, I stopped. Completely. So, two weeks in, this is why: (keep in mind, each week calls for a higher dose) - Awful, AWFUL insomnia began during second week. - word dropping, forgetfulness - hot flashes, sweating, always feeling too warm - lethargic, no energy - Dry mouth. I mean Sahara desert dry! (Interestingly, did not induce a craving for water). Did it curb cravings? Not sure. I don't think so, but if did a little, it still is not worth the high degree of downside."

   
2.0

Maggie (taken for less than 1 month) March 27, 2018

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Contrave (bupropion / naltrexone) for Weight Loss: "The reviews made me skeptical. Most reviews cited nausea as a major side effect. The doctor assured me that only 1/4 users experience this. Ok. First week nothing , almost even felt really happy l! Week two increased dosage and felt extremely foggy, tired , nausea and vision problems. No thank you! No amount of weight loss is worth feeling that awful. After again reading the literature it looks like this drug would only help lose 5% of body weight over a years time. That’s only ten pounds for a two hundred pound person. They need to go re-tweak this drug. I feel horrible and I hope when I don’t take it tomorrow I won’t end up feeling worse yet."

   
4.0

Anonymous (taken for less than 1 month) March 25, 2018

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Contrave (bupropion / naltrexone) for Weight Loss: "I can't brag enough about this magical pill. It has encouraged me to stop smoking, stop over eating, eating out of boredom, It also has helped me to eat healthier and to exercise..."

   
10

Lennie jo barnes (taken for 6 months to 1 year) March 22, 2018

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Contrave (bupropion / naltrexone) for Obesity: "I'm now on day 1 of the full dose, week 4. So far my experience has been mixed. I had SEVERE withdrawal type symptoms, though I'm not addicted to anything. Full disclosure: I had just tapered off of my prescribed antidepressant in order to take this medication which has one built in. This is most likely why several people are experiencing the downs, it gets worse before it gets better as with most antidepressants. However, after the first intense week of dizziness and headache etc, the only real lingering side effects is irregularity (constipation) and occasional sleepiness. I haven't lost any weight, yet. I GAINED 5 pounds at first which is NOT me. I have lost those initial pounds gained though. It has SLIGHTLY adjusted my craving/appetite level. I had lost 50+ pounds in the past using diet pills (discontinued ACE) so I know REAL appetite suppressants and his isn't it. I'm sticking with it in hopes that it will eventually help more, for now."

Carlie March 20, 2018

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Contrave (bupropion / naltrexone) for Obesity: "I am very happy! I started out feeling dizzy and not great the first few days, but I stuck with it. After 2 weeks I am down 6 lbs. I have less cravings and feel full sooner. Whatever this pill is telling my brain to do...I love it! :) I am thinking positively and feel that by summer I will be wearing the clothes that were too tight last summer with ease! My pants already feel better!...less muffin top! YAY! :) I want to lose 24 more pounds in total. I don't feel hopeless anymore with weight loss. I wish everyone the best who is trying this! :)"

   
10

Judy63 (taken for less than 1 month) March 20, 2018

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Contrave (bupropion / naltrexone) for Obesity: "This medication was horrible to and for me. It made me crazy, sobbing multiple times per day. Hostile. Depressed. Nauseous every day within hours of taking the pills. Blurred vision with sensitivity to light. Also found myself binge eating without remorse. I can’t just say that Contrave did not work for me, but it did the opposite of what I expected. Thank you for helping me gain weight!! I advise anyone to avoid taking this medication."

   
1.0

Katsy (taken for 1 to 6 months) March 19, 2018

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Contrave (bupropion / naltrexone) for Obesity: "I was only on Contrave for a week so I can’t speak on how well it worked. The reason I was only on it for a week was due to the side effects. I had debilitating nausea that meds wouldn’t touch. I kept telling myself it would get better but yesterday I threw up several times and it was interfering with my job so I just had to quit contrave. It felt like a combination of being hung over and having a stomach bug for a whole week. I'm so bummed I had to quit due to the side effects."

   
2.0

Liz (taken for less than 1 month) March 19, 2018

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