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Diabetes Insipidus

Medically reviewed by Last updated on Jul 7, 2024.

What is diabetes insipidus?

Diabetes insipidus (DI) is a disease that causes frequent urination. The amount of urine you make is controlled by antidiuretic hormone (ADH). ADH is made in a part of the brain called the hypothalamus. ADH is stored and released by the pituitary gland. The 2 most common types of diabetes insipidus are central and nephrogenic.

What causes central DI?

Central DI (CDI) occurs when your body does not make or release enough ADH. CDI can be caused by any of the following:

What causes nephrogenic DI?

Nephrogenic DI (NDI) occurs when your kidneys do not respond properly to the release of ADH. NDI can be caused by any of the following:

What other signs and symptoms may I have with DI?

How is diabetes insipidus diagnosed?

Your healthcare provider will ask about your symptoms and any health problems you have. Tell your healthcare provider if you have any family members who have DI. Also tell him what medicines you take, and how long you have been taking them. You may also need any of the following:

How is diabetes insipidus treated?

Treatment depends on the type of DI you have and the cause. If you have CDI, you may receive medicine that is similar to ADH to help decrease urination. If have NDI that is caused by a certain medicine, your healthcare provider may have you stop taking that medicine. If your NDI is caused by a disease, your healthcare provider will work with you to treat that disease. You may also need medicine that helps your kidneys control the amount you urinate.

Treatment options

The following list of medications are related to or used in the treatment of this condition.

View more treatment options

How do I manage my symptoms?

When should I contact my healthcare provider?

When should I seek immediate care or call 911?

Care Agreement

You have the right to help plan your care. Learn about your health condition and how it may be treated. Discuss treatment options with your healthcare providers to decide what care you want to receive. You always have the right to refuse treatment. The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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Further information

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