Generic Name: Zidovudine Syrup (zye DOE vue deen)
Brand Name: Retrovir
Medically reviewed on May 2, 2018.
- This medicine may have unsafe effects on the bone marrow. This includes low white blood cell counts and very bad anemia. The bone marrow may not be able to make cells found in the blood as well as it used to.
- This medicine may cause muscle aches and stiffness if it is used for long periods of time. Closely read the part in this leaflet that lists when to call the doctor.
- This medicine may rarely cause swollen liver and an acid health problem in the blood. This may be deadly in some cases. The chance may be higher in women, in overweight people, and in people who have taken drugs like this one for a long time. Talk with your doctor.
Uses of Zidovudine Syrup:
- It is used to treat HIV infection.
- It is used to keep the HIV infection from passing from the mother to the newborn during delivery. The newborn will also be given zidovudine syrup after birth.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Zidovudine Syrup?
- If you have an allergy to zidovudine or any other part of zidovudine syrup.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are taking any of these drugs: Doxorubicin, ribavirin, or stavudine.
- If you are breast-feeding. Do not breast-feed while you take zidovudine syrup.
This is not a list of all drugs or health problems that interact with zidovudine syrup.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take zidovudine syrup with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Zidovudine Syrup?
For all patients taking zidovudine syrup:
- Tell all of your health care providers that you take zidovudine syrup. This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- A change in body fat may happen with zidovudine syrup. You will need to be checked for any changes in body fat while you take zidovudine syrup. If you have questions, talk with your doctor.
- This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
- If you have hepatitis C and HIV, talk with your doctor. Liver function has gotten worse in people who were taking zidovudine syrup and interferon alfa with or without ribavirin. Sometimes, this has been deadly.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using zidovudine syrup while you are pregnant.
For patients taking zidovudine syrup to treat HIV infection:
- This medicine is not a cure for HIV. Stay under the care of your doctor.
How is this medicine (Zidovudine Syrup) best taken?
Use zidovudine syrup as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Keep taking zidovudine syrup as you have been told by your doctor or other health care provider, even if you feel well.
- It is important that you do not miss or skip a dose of zidovudine syrup during treatment.
- Measure liquid doses carefully. Use the measuring device that comes with zidovudine syrup. If there is none, ask the pharmacist for a device to measure zidovudine syrup.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- If you are not sure what to do if you miss a dose, call your doctor.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
For all uses of zidovudine syrup:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of too much lactic acid in the blood (lactic acidosis) like fast breathing, fast heartbeat, a heartbeat that does not feel normal, very bad upset stomach or throwing up, feeling very sleepy, shortness of breath, feeling very tired or weak, very bad dizziness, feeling cold, or muscle pain or cramps.
- Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
- Feeling very tired or weak.
- Muscle pain or weakness.
- Any unexplained bruising or bleeding.
- Change in body fat.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
For patients taking zidovudine syrup to treat HIV infection:
- Changes in your immune system can happen when you start taking drugs to treat HIV. If you have an infection that you did not know you had, it may show up when you take zidovudine syrup. Tell your doctor right away if you have any new signs after you start zidovudine syrup, even after taking it for several months. This includes signs of infection like fever, sore throat, weakness, cough, or shortness of breath.
What are some other side effects of Zidovudine Syrup?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Hard stools (constipation).
- Not hungry.
- Upset stomach or throwing up.
- Feeling tired or weak.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Zidovudine Syrup?
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about zidovudine syrup, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about zidovudine
- Zidovudine Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- 0 Reviews – Add your own review/rating
- Drug class: nucleoside reverse transcriptase inhibitors (NRTIs)
- Zidovudine injection
- Zidovudine Capsules and Tablets
- Zidovudine (Advanced Reading)
- Zidovudine Intravenous (Advanced Reading)
Other brands: Retrovir