Generic Name: atazanavir (A-ta-ZAN-a-vir)
Brand Name: Reyataz
Reyataz is used for:
Treating HIV infection along with other medicines.
Reyataz is an HIV protease inhibitor. It works by blocking the growth of HIV.
Do NOT use Reyataz if:
- you are allergic to any ingredient in Reyataz
- you have severe liver problems
- you are taking alfuzosin, cisapride, an ergot derivative (eg, ergotamine), indinavir, irinotecan, lovastatin, nevirapine, oral midazolam, pimozide, rifampin, salmeterol, simvastatin, St. John's wort, or triazolam
- you are taking sildenafil for pulmonary arterial hypertension (PAH)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Reyataz:
Some medical conditions may interact with Reyataz. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have hemophilia, diabetes or high blood sugar, high cholesterol, an irregular heartbeat, gallbladder problems (eg, gallstones), or liver problems (eg, hepatitis B or C)
- if you have kidney problems or kidney stones or you are on dialysis
Some MEDICINES MAY INTERACT with Reyataz. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Many prescription and nonprescription medicines (eg, used for aches and pains, allergies, angina, asthma or other lung or breathing problems, birth control, blood thinning, blood vessel problems, cancer, Cushing syndrome, cystic fibrosis, depression or other mental or mood problems, diabetes, enlarged prostate gland, erectile dysfunction, gout, heartburn or reflux disease, hepatitis C, high blood pressure, high cholesterol, HIV, immune system suppression, infections, inflammation, irregular heartbeat or other heart problems, low blood sodium levels, migraine, nausea and vomiting, opioid addiction, overactive bladder, pulmonary hypertension, seizures, sleep aid, Tourette disorder), multivitamin products, and herbal or dietary supplements (eg, St. John's wort) because they may interact with Reyataz. Ask your doctor or pharmacist if you are unsure if any of your medicines might interact with Reyataz
This may not be a complete list of all interactions that may occur. Ask your health care provider if Reyataz may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Reyataz:
Use Reyataz as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Reyataz. Talk to your pharmacist if you have questions about this information.
- Take Reyataz by mouth with food.
- Swallow Reyataz whole. Do not break, crush, open, or chew before swallowing.
- If you also take an H2 antagonist (eg, cimetidine) or a proton pump inhibitor (PPI) (eg, omeprazole), talk with your doctor about how to take it with Reyataz.
- If you also take an antacid or didanosine, take Reyataz at least 2 hours before or 1 hour after the antacid or didanosine.
- Take Reyataz on a regular schedule to get the most benefit from it.
- Taking Reyataz at the same time each day will help you remember to take it.
- Continue to use Reyataz even if you feel well. Do not miss any doses.
- If you miss a dose of Reyataz, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Reyataz.
Important safety information:
- Tell your doctor or dentist that you take Reyataz before you receive any medical or dental care, emergency care, or surgery.
- Reyataz interacts with many other medicines. The risk of Reyataz's side effects may be increased or Reyataz's effectiveness may be decreased. The risk of the other medicines' side effects may also be increased. This may include severe, life-threatening, or fatal side effects. Check with your doctor and pharmacist to make sure that it is safe for you to take Reyataz with all of your other medicines (prescription or OTC, natural products, vitamins).
- Reyataz is not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.
- When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Reyataz, even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.
- Reyataz does not stop the spread of HIV to others through blood or sexual contact. Do not have any kind of sex without protection (eg, latex or polyurethane condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors. Talk with your health care provider about ways to prevent the spread of HIV to others.
- Do NOT take more than the recommended dose, change your dose, or stop taking Reyataz without checking with your doctor.
- Changes in body fat (eg, an increased amount of fat in the upper back, neck, breast, and trunk, and loss of fat from the legs, arms, and face) may occur in some patients taking Reyataz. The cause and long-term effects of these changes are unknown. Discuss any concerns with your doctor.
- Hormonal birth control (eg, birth control pills) may not work as well while you are using Reyataz. To prevent pregnancy, use an extra form of birth control (eg, condoms).
- Reyataz may improve immune system function. This may reveal hidden infections in some patients. Tell your doctor right away if you notice symptoms of an infection (eg, fever, sore throat, weakness, cough, shortness of breath) or any other unusual symptoms after you start Reyataz.
- Mild rashes without other symptoms have been reported in patients that take Reyataz. These rashes usually go away within 2 weeks with no change in treatment. Contact your doctor if a rash occurs. Rashes may also occur along with other serious and sometimes fatal symptoms. Contact your doctor right away if you experience a rash along with blisters, fever, general ill feeling, mouth sores, muscle or joint aches, red or swollen eyes, shortness of breath, swelling of your face, symptoms of kidney problems (eg, decreased urination), or symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, yellowing of the eyes or skin).
- Reyataz may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
- Diabetes patients - Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Hemophilia patients - Some people with hemophilia have developed increased bleeding while taking protease inhibitors, such as Reyataz. Report all bleeding episodes to your doctor.
- Lab tests, including liver function, bilirubin levels, CD4 count, and lipid or cholesterol levels, may be performed while you use Reyataz. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Reyataz should not be used in CHILDREN younger than 3 months old; a type of brain damage caused by high blood bilirubin levels (kernicterus) may occur.
- Reyataz should not be used in CHILDREN who weigh less than 22 lb (10 kg) or more than 55 lb (25 kg).
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Reyataz while you are pregnant. It is not known if this medicine is found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Reyataz to the baby.
Possible side effects of Reyataz:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Cough; diarrhea; headache; mild stomach pain; muscle pain; nausea; stuffy or runny nose; trouble sleeping; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; burning, numbness, or tingling; dark urine; depression; dizziness; fever, chills, or sore throat; irregular heartbeat; light-headedness; painful urination; pale stools; persistent loss of appetite; red, swollen, blistered, or peeling skin; severe stomach or back pain (with or without nausea or vomiting); side pain; swelling of the hands, ankles, or feet; unusual bleeding or bruising; wheezing; yellowing of skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Reyataz:
Store Reyataz at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Reyataz out of the reach of children and away from pets.
- If you have any questions about Reyataz, please talk with your doctor, pharmacist, or other health care provider.
- Reyataz is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Reyataz or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Reyataz. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Reyataz. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Reyataz.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Reyataz (atazanavir)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
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- Generic Availability
- Drug class: protease inhibitors