Generic Name: Rasburicase (ras BYOOR i kayse)
Brand Name: Elitek
Medically reviewed by Drugs.com. Last updated on Sep 28, 2019.
- Severe allergic reactions have happened with rasburicase. Sometimes, this has been deadly. Tell your doctor about any chest pain or tightness, itching, rash, severe dizziness or passing out, or shortness of breath or other breathing problems.
- This medicine may cause unsafe red blood cell problems called hemolysis and methemoglobinemia. If either of these health problems happens with rasburicase, do not take rasburicase again. Talk with your doctor.
- People with an enzyme deficiency called G6PD deficiency may have more chance of getting hemolysis. Do not take rasburicase if you have G6PD deficiency. You may need to be screened for G6PD deficiency before taking rasburicase. Talk with your doctor.
- This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take rasburicase.
Uses of Rasburicase:
- It is used to treat or prevent high uric acid levels during chemo.
What do I need to tell my doctor BEFORE I take Rasburicase?
- If you are allergic to rasburicase; any part of rasburicase; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are breast-feeding. Do not breast-feed while you take rasburicase and for 2 weeks after your last dose.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take rasburicase with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Rasburicase?
- Tell all of your health care providers that you take rasburicase. This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant. If you are pregnant or you get pregnant while taking rasburicase, call your doctor right away.
How is this medicine (Rasburicase) best taken?
Use rasburicase as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of methemoglobinemia like a blue or gray color of the lips, nails, or skin; a heartbeat that does not feel normal; seizures; very bad dizziness or passing out; very bad headache; feeling very sleepy; feeling tired or weak; or shortness of breath. This effect is rare but may be deadly if it happens.
- Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
- Feeling very tired or weak.
- Pale skin.
- Dark urine or yellow skin or eyes.
- Swelling in the arms or legs.
What are some other side effects of Rasburicase?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Constipation, diarrhea, stomach pain, upset stomach, or throwing up.
- Sore throat.
- Mouth irritation or mouth sores.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Rasburicase?
- If you need to store rasburicase at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about rasburicase, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about rasburicase
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- Drug class: antihyperuricemic agents
Other brands: Elitek