Generic Name: Physostigmine (fye zoe STIG meen)
Medically reviewed on Feb 20, 2019
Uses of Physostigmine:
- It is used to reverse the effects of some drugs.
- It is used to treat some overdoses.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Physostigmine?
- If you have an allergy to physostigmine or any other part of physostigmine.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have any of these health problems: Asthma, high blood sugar (diabetes), heart disease, bowel block, or trouble passing urine.
- If you have dead body tissue from lowered blood flow or an infection (gangrene).
- If you are using atropine.
This is not a list of all drugs or health problems that interact with physostigmine.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take physostigmine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Physostigmine?
- Tell all of your health care providers that you take physostigmine. This includes your doctors, nurses, pharmacists, and dentists.
- If you are allergic to sulfites, talk with your doctor. Some products have sulfites.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using physostigmine while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Physostigmine) best taken?
Use physostigmine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a muscle or vein.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Upset stomach or throwing up.
- Severe diarrhea.
- Passing urine more often.
- More saliva.
- Sweating a lot.
- Slow heartbeat.
What are some other side effects of Physostigmine?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Physostigmine?
- If you need to store physostigmine at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about physostigmine, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about physostigmine
- Physostigmine Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: antidotes
Other brands: Antilirium
- Physostigmine Salicylate (AHFS Monograph)
- Physostigmine Injection (FDA)
- Physostigmine (Wolters Kluwer)