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Physostigmine Side Effects

For the Consumer

Applies to physostigmine: parenteral injection

Side effects include:

Nausea, vomiting, epigastric pain, miosis, salivation, sweating, lacrimation, dyspnea, bronchospasm.

For Healthcare Professionals

Applies to physostigmine: injectable solution

Gastrointestinal

Frequency not reported: Nausea, vomiting, hypersalivation[Ref]

Nausea, vomiting, and salivation can be offset by a reduction in dosage.[Ref]

Cardiovascular

Frequency not reported: Bradycardia[Ref]

Bradycardia may occur if intravenous administration is too rapid.[Ref]

Nervous system

Convulsions may occur if intravenous administration is too rapid.[Ref]

Frequency not reported: Convulsions[Ref]

References

1. Cerner Multum, Inc. "Australian Product Information." O 0

2. "Product Information. Physostigmine Salicylate (physostigmine)." Taylor Pharmaceuticals, Buffalo Grove, IL.

It is possible that some side effects of physostigmine may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

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