Generic Name: Omacetaxine (oh ma se TAX een)
Brand Name: Synribo
Medically reviewed on May 2, 2018.
Uses of Omacetaxine:
- It is used to treat a type of leukemia.
What do I need to tell my doctor BEFORE I take Omacetaxine?
- If you have an allergy to omacetaxine or any other part of omacetaxine.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have high blood sugar (diabetes).
- If you are breast-feeding. Do not breast-feed while you take omacetaxine.
This is not a list of all drugs or health problems that interact with omacetaxine.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take omacetaxine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Omacetaxine?
- Tell all of your health care providers that you take omacetaxine. This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how omacetaxine affects you.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine may lower the ability of your bone marrow to make blood cells that your body needs. This can lead to needing a blood transfusion and very bad and sometimes deadly bleeding problems or infections. Tell your doctor right away if you have signs of infection like fever, chills, or sore throat; any bruising or bleeding; or if you feel very tired or weak.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- If you have high blood sugar (diabetes), talk with your doctor. This medicine may raise blood sugar.
- Check your blood sugar as you have been told by your doctor.
- Constipation, diarrhea, throwing up, and upset stomach are common with omacetaxine. If these happen, talk with your doctor about ways to lower these side effects. Call your doctor right away if any of these effects bother you, do not go away, or get very bad.
- This medicine may cause harm if swallowed. If omacetaxine is swallowed, call a doctor or poison control center right away.
- If you are 65 or older, use omacetaxine with care. You could have more side effects.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant.
- Use birth control that you can trust to prevent pregnancy while taking omacetaxine.
- If you are pregnant or you get pregnant while taking omacetaxine, call your doctor right away.
How is this medicine (Omacetaxine) best taken?
Use omacetaxine as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into the fatty part of the skin.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Follow how to use as you have been told by the doctor or read the package insert.
- Your pharmacist will need to mix omacetaxine before you get it.
- You will need to take special care when handling omacetaxine. Check with the doctor or pharmacist to see how to handle omacetaxine.
- Move the site where you give the shot with each shot.
- Do not give into skin that is irritated, bruised, red, infected, or scarred.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
- If you get omacetaxine on the skin, wash it off right away with soap and water.
- If you get omacetaxine in the eyes, flush right away with cool water and get medical help.
What do I do if I miss a dose?
- Skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Feeling very tired or weak.
- Shortness of breath.
- Very bad belly pain.
- Swelling in the arms or legs.
What are some other side effects of Omacetaxine?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Belly pain.
- Feeling tired or weak.
- Not hungry.
- Muscle or joint pain.
- Back pain.
- Hair loss.
- Not able to sleep.
- Irritation where the shot is given.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Omacetaxine?
- Most of the time, omacetaxine will be given in a hospital or doctor's office. If stored at home, follow how to store as you were told by the doctor.
- Be sure you know how long you can store omacetaxine if stored in a refrigerator or at room temperature.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time omacetaxine is refilled. If you have any questions about omacetaxine, please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about omacetaxine
- Omacetaxine Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
- 0 Reviews – Add your own review/rating
- Drug class: miscellaneous antineoplastics
Other brands: Synribo