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Naloxone auto-injector

Pronunciation

Generic Name: naloxone (nal-OX-one)
Brand Name: Evzio

Naloxone auto-injector is used for:

Treating opioid overdose.

Naloxone auto-injector is an opioid antagonist. It works by blocking opiate receptor sites, which reverses or prevents the toxic effects of opioid pain medicines.

Do NOT use naloxone auto-injector if:

  • you are allergic to any ingredient in naloxone auto-injector

Contact your doctor or health care provider right away if any of these apply to you.

Before using naloxone auto-injector:

Some medical conditions may interact with naloxone auto-injector. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart problems or a history of substance abuse

Some MEDICINES MAY INTERACT with naloxone auto-injector. However, no specific interactions are known at this time.

Ask your health care provider if naloxone auto-injector may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use naloxone auto-injector:

Use naloxone auto-injector as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet and instructions for use are available with naloxone auto-injector. Talk to your pharmacist if you have questions about this information.
  • A health care provider will teach you how to use naloxone auto-injector. Be sure you understand how to use naloxone auto-injector. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Someone else will usually have to give you the injection. Be sure those around you know where naloxone auto-injector is stored and how to give it if needed.
  • Use the proper technique taught to you by your doctor. Inject naloxone auto-injector only into the outer thigh as directed by your doctor. Do NOT inject it into a vein.
  • Check naloxone auto-injector regularly. Replace naloxone auto-injector if the expiration date has passed; if it contains particles, is cloudy, or is discolored; or if the container is cracked or damaged.
  • Each auto-injector has only 1 dose. If another dose is needed, you will need to use a second auto-injector.
  • Get emergency medical help right after use, even if you wake up. You may need further medical attention. Be sure the doctor or health care provider knows that you have received an injection of naloxone auto-injector.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • Naloxone auto-injector is usually given in an emergency situation. If you are unable to use naloxone auto-injector, seek medical attention right away.
  • If you miss a dose of naloxone auto-injector, seek medical attention right away.

Ask your health care provider any questions you may have about how to use naloxone auto-injector.

Important safety information:

  • Tell your doctor or dentist that you take naloxone auto-injector before you receive any medical or dental care, emergency care, or surgery.
  • In infants younger than 4 weeks old who have been getting opioid medicines on a regular basis, sudden withdrawal may be life-threatening if not treated right away. Call the doctor right away if your child has a seizure, is crying more than usual, or has increased reflexes.
  • If naloxone auto-injector is used during pregnancy, it may cause withdrawal in the unborn baby. A doctor will need to check on your unborn baby after you use naloxone auto-injector.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using naloxone auto-injector while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use naloxone auto-injector, check with your doctor. Discuss any possible risks to your baby.

If you are addicted to opioid medicines and are given naloxone auto-injector, you may experience WITHDRAWAL symptoms, including abnormal skin sensations; anxiety; diarrhea; fever; goose bumps; nausea; pain; rapid heartbeat; rigid muscles; runny nose; seeing, hearing, or feeling things that are not there; seizures; shivering or tremors; sneezing; sweating; trouble sleeping; and vomiting.

Possible side effects of naloxone auto-injector:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain or pressure; fainting; fast or irregular heartbeat; seizures; severe or persistent dizziness or headache; shortness of breath.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of naloxone auto-injector:

Store naloxone auto-injector at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Do not freeze. Store in the storage case that comes with naloxone auto-injector. Store away from heat, moisture, and light. Do not store in the bathroom. Keep naloxone auto-injector out of the reach of children and away from pets.

General information:

  • If you have any questions about naloxone auto-injector, please talk with your doctor, pharmacist, or other health care provider.
  • Naloxone auto-injector is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take naloxone auto-injector or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about naloxone auto-injector. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to naloxone auto-injector. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using naloxone auto-injector.

Review Date: August 8, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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