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Hydroxyamphetamine/ tropicamide

Generic Name: hydroxyamphetamine/tropicamide (hye-drox-ee-am-FE-ta-meen/troe-PIK-a-mide)
Brand Name: Paremyd

Hydroxyamphetamine/ tropicamide is used for:

Dilating the pupil and paralyzing certain muscles in the eye for diagnostic tests. It may also be used for other conditions as determined by your doctor.

Hydroxyamphetamine/tropicamide is a sympathomimetic and anticholinergic combination eye drop. It works by relaxing the muscles of the eye to cause the pupil to dilate or widen (mydriasis).

Do NOT use hydroxyamphetamine/ tropicamide if:

  • you are allergic to any ingredient in hydroxyamphetamine/tropicamide
  • you have angle-closure glaucoma or are at risk for developing angle-closure glaucoma

Contact your doctor or health care provider right away if any of these apply to you.

Before using hydroxyamphetamine/ tropicamide:

Some medical conditions may interact with hydroxyamphetamine/tropicamide. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have high blood pressure, an overactive thyroid, diabetes, heart problems, an irregular heartbeat, or glaucoma or you are at risk for glaucoma

Some MEDICINES MAY INTERACT with hydroxyamphetamine/tropicamide. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • Carbachol, ophthalmic cholinesterase inhibitors (eg, echothiophate), or pilocarpine because their effectiveness may be decreased by hydroxyamphetamine/tropicamide

This may not be a complete list of all interactions that may occur. Ask your health care provider if hydroxyamphetamine/tropicamide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use hydroxyamphetamine/ tropicamide:

Use hydroxyamphetamine/tropicamide as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Remove contact lenses before using hydroxyamphetamine/tropicamide.
  • To use hydroxyamphetamine/tropicamide in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 2 to 3 minutes. Do not blink. Keep your eyes closed for 2 to 3 minutes. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
  • Hydroxyamphetamine/tropicamide is only for the eye. Do not get it in your nose or mouth.
  • Wash your hands after using hydroxyamphetamine/tropicamide. If the patient is a child, wash the child's hands as well.
  • If you miss a dose of hydroxyamphetamine/tropicamide, contact your doctor right away.

Ask your health care provider any questions you may have about how to use hydroxyamphetamine/tropicamide.

Important safety information:

  • Hydroxyamphetamine/tropicamide may cause blurred vision or sensitivity to sunlight. Wear sunglasses if you are outside in the bright sunlight. Use hydroxyamphetamine/tropicamide with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • If you have an appointment for an eye examination and your doctor has told you that you will receive hydroxyamphetamine/tropicamide, be sure to make arrangements to have someone drive you home in case your vision is blurry.
  • Hydroxyamphetamine/tropicamide may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.
  • Pupil dilation usually reverses within 6 to 8 hours after use, but may last as long as 24 hours.
  • Use hydroxyamphetamine/tropicamide with caution in the ELDERLY; they may be more sensitive to its effects.
  • Caution is advised when using hydroxyamphetamine/tropicamide in CHILDREN; they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using hydroxyamphetamine/tropicamide while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use hydroxyamphetamine/tropicamide, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of hydroxyamphetamine/ tropicamide:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; burning; dry mouth; headache; nausea; sensitivity to sunlight; temporary stinging.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); behavioral changes, especially in children; eye pain; irregular or rapid heartbeat; mental or mood changes, especially in children; paleness or flushing of the skin; rigid muscles; shortness of breath; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of hydroxyamphetamine/tropicamide:

Store hydroxyamphetamine/tropicamide at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep hydroxyamphetamine/tropicamide out of the reach of children and away from pets.

General information:

  • If you have any questions about hydroxyamphetamine/tropicamide, please talk with your doctor, pharmacist, or other health care provider.
  • Hydroxyamphetamine/tropicamide is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take hydroxyamphetamine/tropicamide or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about hydroxyamphetamine/tropicamide. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to hydroxyamphetamine/tropicamide. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using hydroxyamphetamine/tropicamide.

Issue Date: June 3, 2015

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.