Generic Name: Deferasirox Tablets For Oral Suspension (de FER a sir ox)
Brand Name: Exjade
- This medicine may cause very bad and sometimes deadly kidney problems. You may be at greater risk if you have a history of kidney problems. You will be watched closely by the doctor. Talk with your doctor.
- This medicine may cause very bad and sometimes deadly liver problems. You may be at greater risk if you have a history of liver problems. You will be watched closely by the doctor. Talk with your doctor.
- If you have kidney or liver problems, talk with your doctor. This medicine may need to be avoided or the dose may need to be changed with certain types of kidney or liver problems.
- This medicine may raise the chance of very bad and sometimes deadly stomach or bowel side effects like ulcers or bleeding. The risk is greater in older people. The risk is also greater in people who have had stomach or bowel ulcers or bleeding before. These problems may occur without warning signs. Talk with the doctor.
Uses of Exjade:
- It is used to get rid of iron when too much is in the body.
What do I need to tell my doctor BEFORE I take Exjade?
- If you have an allergy to deferasirox or any other part of Exjade (deferasirox tablets for oral suspension).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have any of these health problems: Cancer, certain blood or bone marrow problems (low platelets, high-risk myelodysplastic syndrome/MDS), kidney disease, or liver disease.
- If you are using another drug like this one.
- If you are breast-feeding or plan to breast-feed.
This is not a list of all drugs or health problems that interact with this medicine.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Exjade with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Exjade?
For all patients taking this medicine:
- Tell all of your health care providers that you take Exjade. This includes your doctors, nurses, pharmacists, and dentists.
- Very bad and sometimes deadly blood cell problems may happen. You will need to have blood tests while you take this medicine. Talk with your doctor. Tell your doctor right away if you have any signs of infection.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how Exjade affects you.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Have an eye exam as you have been told by your doctor.
- Have a hearing test before starting this medicine and while you take Exjade.
- Do not take antacids that have aluminum in them with this medicine.
- Do not switch between different forms of Exjade without first talking with the doctor.
- This medicine may affect how much of some other drugs are in your body. If you are taking other drugs, talk with your doctor. You may need to have your blood work checked more closely while taking this medicine with your other drugs.
- If you are 65 or older, use Exjade with care. You could have more side effects.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking this medicine.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Exjade (deferasirox tablets for oral suspension) while you are pregnant.
- If giving to your child, the dose of this medicine may need to be changed as your child's weight changes. Have your child's weight checked often. Talk with the doctor before changing your child's dose.
How is this medicine (Exjade) best taken?
Use Exjade as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take on an empty stomach. Take 30 minutes before a meal.
- Mix the tablet with fruit juice (orange, apple) or water until melted and drink right away. Do not chew or swallow it whole.
- After drinking, rinse the rest of the drug in the glass with more juice or water and drink.
- Take this medicine at the same time of day.
- To gain the most benefit, do not miss doses.
- Keep taking Exjade as you have been told by your doctor or other health care provider, even if you feel well.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Feeling very tired or weak.
- Change in hearing.
- Hearing loss.
- Change in eyesight.
- Very bad belly pain.
- Rashes may happen with this medicine. This medicine may need to be stopped for some types of rashes. If you get a rash while taking Exjade, call your doctor right away to find out what to do.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
What are some other side effects of Exjade?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Belly pain.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Exjade?
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take Exjade or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Exjade. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
Review Date: October 4, 2017
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- Drug class: chelating agents