Carbamazepine Extended-Release Tablets
Generic name: Carbamazepine Extended-Release Tablets [ kar-ba-MAZ-e-peen ]
Brand name: Tegretol XR
Drug class: Dibenzazepine anticonvulsants
Medically reviewed by Drugs.com. Last updated on Apr 23, 2024.
Warning
- Unsafe blood cell count problems have happened, like aplastic anemia and a type of low white blood cell count. Tell your doctor right away if you feel very tired or weak, or have a fever, chills, shortness of breath, any unexplained bruising or bleeding, or purple "splotches" on your skin.
- Call your doctor right away if you have any signs of infection like fever, chills, flu-like signs, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or a wound that will not heal.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- People with a certain gene (HLA-B*1502) have a higher chance of severe and sometimes deadly skin reactions with this medicine (carbamazepine extended-release tablets). This gene is more common in Asian people. If you have questions, talk with the doctor.
Uses of Carbamazepine Extended-Release Tablets:
- It is used to treat seizures.
- It is used to treat pain caused by a problem with a nerve in the face.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Carbamazepine Extended-Release Tablets?
- If you are allergic to this medicine (carbamazepine extended-release tablets); any part of this medicine (carbamazepine extended-release tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have kidney disease.
- If you have had any of these health problems: Bone marrow disease or porphyria.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with this medicine (carbamazepine extended-release tablets), like certain drugs that are used for hepatitis C, HIV, or infections. There are many drugs that must not be taken with this medicine (carbamazepine extended-release tablets).
- If you have taken certain drugs for depression or Parkinson's disease in the last 14 days. This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen.
- If you are breast-feeding or plan to breast-feed.
This is not a list of all drugs or health problems that interact with this medicine (carbamazepine extended-release tablets).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (carbamazepine extended-release tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Carbamazepine Extended-Release Tablets?
- Tell all of your health care providers that you take this medicine (carbamazepine extended-release tablets). This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine (carbamazepine extended-release tablets) affects you.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Have an eye exam as you have been told by your doctor.
- This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take this medicine (carbamazepine extended-release tablets).
- This medicine may cause the results of some pregnancy tests to be wrong. Talk with the doctor.
- Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
- If you drink grapefruit juice or eat grapefruit often, talk with your doctor.
- A severe and sometimes deadly reaction has happened. Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. If you have questions, talk with the doctor.
- Patients who take this medicine (carbamazepine extended-release tablets) may be at a greater risk of having thoughts or actions of suicide. The risk may be greater in people who have had these thoughts or actions in the past. Call the doctor right away if signs like low mood (depression), nervousness, restlessness, grouchiness, panic attacks, or changes in mood or actions are new or worse. Call the doctor right away if any thoughts or actions of suicide occur.
- Heart problems like heart failure and certain very bad abnormal heartbeats have happened with this medicine (carbamazepine extended-release tablets). Sometimes, these heart problems have been deadly. Call your doctor right away if you have a fast or abnormal heartbeat; very bad dizziness or passing out; or shortness of breath, a big weight gain, or swelling in the arms or legs.
- A very bad reaction called angioedema has happened with this medicine (carbamazepine extended-release tablets). Sometimes, this may be life-threatening. Signs may include swelling of the hands, face, lips, eyes, tongue, or throat; trouble breathing; trouble swallowing; or unusual hoarseness. Get medical help right away if you have any of these signs.
- If you are 65 or older, use this medicine (carbamazepine extended-release tablets) with care. You could have more side effects.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking this medicine (carbamazepine extended-release tablets).
- This medicine may cause harm to the unborn baby if you take it while you are pregnant. If you are pregnant or you get pregnant while taking this medicine (carbamazepine extended-release tablets), call your doctor right away.
How is this medicine (Carbamazepine Extended-Release Tablets) best taken?
Use this medicine (carbamazepine extended-release tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Do not stop taking this medicine (carbamazepine extended-release tablets) all of a sudden without calling your doctor. You may have a greater risk of seizures. If you need to stop this drug, you will want to slowly stop it as ordered by your doctor.
- Keep taking this medicine (carbamazepine extended-release tablets) as you have been told by your doctor or other health care provider, even if you feel well.
- Take with food.
- Swallow whole. Do not chew, break, or crush.
- Do not take chipped or broken tablets.
- You may see the tablet shell in your stool. This is normal and not a cause for concern.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
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What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of low sodium levels like headache, trouble focusing, memory problems, feeling confused, weakness, seizures, or change in balance.
- Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- If seizures are worse or not the same after starting this medicine (carbamazepine extended-release tablets).
- Change in speech.
- Hallucinations (seeing or hearing things that are not there).
- Not able to control eye movements.
- Slow heartbeat.
- Change in eyesight.
- Swelling, warmth, numbness, change of color, or pain in a leg or arm.
- Swollen gland.
- Very bad muscle or joint pain.
- Trouble controlling body movements.
- A burning, numbness, or tingling feeling that is not normal.
- A very bad and sometimes deadly health problem called neuroleptic malignant syndrome (NMS) may happen. Call your doctor right away if you have any fever, muscle cramps or stiffness, dizziness, very bad headache, confusion, change in thinking, fast heartbeat, heartbeat that does not feel normal, or are sweating a lot.
What are some other side effects of Carbamazepine Extended-Release Tablets?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling dizzy, sleepy, tired, or weak.
- Upset stomach or throwing up.
- Dry mouth.
- Constipation.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Carbamazepine Extended-Release Tablets?
- Store at room temperature protected from light. Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine (carbamazepine extended-release tablets) is refilled. If you have any questions about this medicine (carbamazepine extended-release tablets), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
More about carbamazepine
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Patient resources
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Professional resources
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- Carbamazepine ER (FDA)
- Carbamazepine Oral Suspension (FDA)
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.